Glioblastoma is known as one of the most aggressive human cancers. To gain access of the
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …

This study developed polymeric nanoparticles (NPs) conjugated with monoclonal antibody
(mAb) for glioblastoma treatment. In this study, the physicochemical properties of poly (butyl …

For effective therapy for glioma, it is essential for chemotherapeutics to pass the blood-brain
barrier to target glioma cells with little side effects to surrounding normal cells. In this study …

Glioblastomas belong to the most devastating cancer diseases. For this reason, polysorbate
80 (Tween 80®)-coated poly (isohexyl cyanoacrylate)(PIHCA)(Monorex®) nanoparticles …

Polybutylcyanoacrylate (PBCA) nanoparticles coated with polysorbate-80 have been
extensively studied for delivery of drugs into the animal models; however, 1% polysorbate …

Poly (alkyl cyanoacrylates) with a higher alkyl chain length is relatively less toxic than those
with a lower alkyl chain length. Several interesting studies were reported on the usefulness …

Poly (n-butyl cyanoacrylate) nanoparticles coated with polysorbate-80 can enable the
transport of bound drugs across the blood–brain barrier (BBB) after iv injection. In the …

Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

This study aims to improve the cytotoxicity and potency of cisplatin-loaded
polybutylcyanoacrylate (PBCA) nanoparticles (NPs) for the treatment of lung cancer through …

Background: This study aimed to develop a novel drug formulation using
polybutylcyanoacrylate (PBCA) nanoparticles to deliver cisplatin, a commonly used …