The rising incidence of diabetes, metabolic syndrome, and subsequent vascular diseases is
now a major public health problem in industrialized countries. New therapeutic strategies to …

A significant increase in the worldwide incidence and prevalence of type 2 diabetic mellitus
(T2DM) has elevated the need for studies on novel and effective therapeutic strategies …

Resveratrol (RESV) exerts important pharmacological effects on human health: in addition to
its beneficial effects on type 2 diabetes and cardiovascular diseases, it also modulates …

Objective—Calorie restriction (CR) prolongs the lifespan of various species, ranging from
yeasts to mice. In yeast, CR extends the lifespan by increasing the activity of silencing …

The rising incidence of type 2 diabetes mellitus (T2DM) is a major public health problem in
industrialized countries, and new therapeutic strategies to prevent T2DM are urgently …

Introduction: Dysregulation of metabolic pathways, caused by imbalances in energy
homeostasis, leads to type 2 diabetes characterized by high glucose concentration in the …

Ageing is the most significant risk factor for a range of prevalent diseases, including cancer,
cardiovascular disease, and diabetes. Accordingly, interventions are needed for delaying or …

Caloric restriction prolongs the lifespan of many species. Therefore, investigators have
researched the usefulness of caloric restriction for healthy lifespan extension. Sirt1, an …

Calorie restriction (CR) is the only experimental manipulation that is known to extend the
lifespan of a number of organisms including yeast, worms, flies, rodents and perhaps non …

The prevalence of type 2 diabetes mellitus (T2DM) has been increasing worldwide.
Therefore, a novel therapeutic strategy by which to prevent T2DM is urgently required …