Abstract Tumor Necrosis Factor α (TNF-α), a multifunctional pro-inflammatory cytokine, is
produced by macrophages/monocytes during acute inflammation, and plays a critical role in …

Parkinson's disease is normally accompanied by excessive inflammation. Myocardial
infraction associated transcript 2 (Mirt2) has an activity to relieve inflammation in numerous …

Mesenchymal stem cells (MSCs) exhibit extensive self‐renewal potential and can modulate
immunocyte activation. Our previous study reported that miR‐181a expression was …

Fine-tuning of inflammatory responses by microRNAs (miRNAs) is complex, as they can
both enhance and repress expression of pro-inflammatory mediators. In this study, we …

IL-10 is a potent anti-inflammatory molecule that, in phagocytes, negatively targets cytokine
expression at transcriptional and posttranscriptional levels. Posttranscriptional checkpoints …

Many microRNAs (miRNAs) are selectively expressed in mammalian immune cells and
have been linked to immune responses in host defense and autoimmune disease. In …

Objectives: Macrophages are conventionally classified as pro-inflammatory (M1) and anti-
inflammatory (M2) functional types. There is evidence for a predominance of macrophages …

Macrophage activation is a central event in immune responses. Macrophages undergoing
classical activation (M1 macrophages) are proinflammatory, whereas alternatively activated …

Although microRNAs were shown to participate in innate immune responses, it is not
completely understood how they regulate negative immunomodulatory events. IL-10 is an …

High levels of miR-23a expression in human primary macrophages suggested that miR-23a
might have an important role in innate immune cells. Therefore, we investigated whether …