Indomethacin augments lipopolysaccharide-induced expression of inflammatory molecules in the mouse brain
MY Mohamed, W Masocha - PeerJ, 2020 - peerj.com
Indomethacin and other non-steroidal anti-inflammatory drugs (NSAIDs) are used to relieve
pain and fever including during infections. However, some studies suggest that NSAIDs …
pain and fever including during infections. However, some studies suggest that NSAIDs …
Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
J Zhao, W Bi, S Xiao, X Lan, X Cheng, J Zhang, D Lu… - Scientific reports, 2019 - nature.com
In this study, we investigated lipopolysaccharide (LPS)-induced cognitive impairment and
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …
Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice
L Yuan, S Liu, X Bai, Y Gao, G Liu, X Wang… - Journal of …, 2016 - Springer
Background Overactivated microglia is involved in various kinds of neurodegenerative
diseases. Suppression of microglial overactivation has emerged as a novel strategy for …
diseases. Suppression of microglial overactivation has emerged as a novel strategy for …
Oleic acid reduces lipopolysaccharide-induced expression of iNOS and COX-2 in BV2 murine microglial cells: Possible involvement of reactive oxygen species, p38 …
YT Oh, JY Lee, J Lee, H Kim, KS Yoon, W Choe… - Neuroscience …, 2009 - Elsevier
Microglia are the major cells involved in neuroinflammation resulting in brain tissue damage
during infection and neurodegenerative diseases. In this study, we examined the effects of …
during infection and neurodegenerative diseases. In this study, we examined the effects of …
Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt
B Xing, T Xin, RL Hunter, G Bing - Journal of neuroinflammation, 2008 - Springer
Background Previous studies have suggested that peroxisome proliferator activated
receptor-gamma (PPAR-γ)-mediated neuroprotection involves inhibition of microglial …
receptor-gamma (PPAR-γ)-mediated neuroprotection involves inhibition of microglial …
Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1β release through the inhibition of Nogo-A …
PK Chao, KT Lu, JY Jhu, YYP Wo, TC Huang… - Journal of …, 2012 - Springer
Background Nogo-A is a member of the reticulon family of membrane-associated proteins
and plays an important role in axonal remodeling. The present study aimed to investigate …
and plays an important role in axonal remodeling. The present study aimed to investigate …
Wortmannin enhances lipopolysaccharide-induced inducible nitric oxide synthase expression in microglia in the presence of astrocytes in rats
H Pyo, MS Yang, I Jou, E Joe - Neuroscience letters, 2003 - Elsevier
Microglia, the primary inflammatory cells in the brain, are activated upon brain injury.
Activated microglia produce nitric oxide (NO), a major toxin to neuronal cells. It has been …
Activated microglia produce nitric oxide (NO), a major toxin to neuronal cells. It has been …
Inhibition of inducible nitric oxide synthase and interleukin-1β expression by tunicamycin in cultured glial cells exposed to lipopolysaccharide
T Hosoi, J Noguchi, M Takakuwa, M Honda, Y Okuma… - Brain research, 2014 - Elsevier
Endoplasmic reticulum (ER) stress has recently been implicated in human diseases such as
Alzheimer׳ s disease (AD) and Parkinson׳ s disease (PD). However, the link between the …
Alzheimer׳ s disease (AD) and Parkinson׳ s disease (PD). However, the link between the …
Accelerated cerebral ischemic injury by activated macrophages/microglia after lipopolysaccharide microinjection into rat corpus callosum
In cerebral ischemic insults, activated inflammatory cells such as microglia and
macrophages may be implicated in the pattern and degree of ischemic injury by producing …
macrophages may be implicated in the pattern and degree of ischemic injury by producing …
Systemic administration of lipopolysaccharide induces cyclooxygenase-2 immunoreactivity in endothelium and increases microglia in the mouse hippocampus
DW Chung, KY Yoo, IK Hwang, DW Kim… - Cellular and molecular …, 2010 - Springer
In this study, we observed the effects of lipopolysaccharide (LPS) on neurodegeneration and
immune response in the hippocampus. LPS is a gram-negative bacterial cell surface …
immune response in the hippocampus. LPS is a gram-negative bacterial cell surface …