Melanin is a major virulence factor in pathogenic fungi that enhances the ability of fungal
cells to resist immune clearance. Cryptococcus neoformans is an important human …

Black melanin-like pigments are produced by several neurotropic fungi, including
Cryptococcus neoformans. Pigment production is associated with virulence. In media …

Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …

The ability of Cryptococcus neoformans to synthesize polymerized melanin in vitro has been
associated with virulence, but it is unclear whether this fungus synthesizes polymerized …

Melanin has been proposed as a virulence factor in Cryptococcus neoformans, but its
presence has not been shown unambiguously in vivo. Validated methods used previously to …

Cryptococcus neoformans is unusual among melanotic fungi in that it requires an
exogenous supply of precursor to synthesize melanin. C. neoformans melanizes during …

Cryptococcus neoformans and Cryptococcus gattii are two species complexes in the large
fungal genus Cryptococcus and are responsible for potentially lethal disseminated …

Cryptococcus neoformans is a fungus that is pathogenic in humans and that can produce
melanin in vitro. Melanization is associated with virulence, but there is no evidence that …

Cryptococcus neoformans melanizes in the environment and in mammalian tissues, but the
process of melanization in either venue is mysterious given that this microbe produces …

Melanin synthesis has been associated with virulence for the human pathogenic fungus
Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize …