Polysaccharide from Flammulina velutipes residues protects mice from Pb poisoning by activating Akt/GSK3β/Nrf-2/HO-1 signaling pathway and modulating gut …

Y Liu, H Li, P Ren, Y Che, J Zhou, W Wang… - International journal of …, 2023 - Elsevier
Lead (Pb) can cause damages to the brain, liver, kidney, endocrine and other systems.
Flammulina velutipes residues polysaccharide (FVRP) has been reported to exhibit anti …

Flammulina velutipes polysaccharide counteracts cadmium-induced gut injury in mice via modulating gut inflammation, gut microbiota and intestinal barrier

R Hao, X Zhou, X Zhao, X Lv, X Zhu, NN Gao… - Science of The Total …, 2023 - Elsevier
Abstract Cadmium (Cd), as Group I carcinogen, can induce damage to various organs
including the gut. It is of great importance to meet the rising demand for effective therapies …

[HTML][HTML] Flammulinavelutipes Polysaccharides Modulate Gut Microbiota and Alleviate Carbon Tetrachloride-Induced Hepatic Oxidative Injury in Mice

Y Xu, Z Zhang, B Wang, X He, J Tang, W Peng… - Frontiers in …, 2022 - frontiersin.org
A carbon tetrachloride-induced acute liver injury mouse model is used to study the
regulation of gut microbiota and hepatoprotective effect of polysaccharides from Flammulina …

Using Cordyceps militaris extracellular polysaccharides to prevent Pb 2+-induced liver and kidney toxicity by activating Nrf2 signals and modulating gut microbiota

Q Song, Z Zhu - Food & function, 2020 - pubs.rsc.org
In this study, we investigated the protective efficacy of extracellular polysaccharide from
Cordyceps militaris (CEP-I) in liver and kidney and their regulating effect on gut microbiota …

Protective effects of a Lachnum polysaccharide against liver and kidney injury induced by lead exposure in mice

G Hou, MM Surhio, H Ye, X Gao, Z Ye, J Li… - International journal of …, 2019 - Elsevier
This study was designed to investigate the liver and kidney protective efficacy of a Lachnum
polysaccharide (LEP) against Pb-induced toxicity in mice. The results showed that LEP …

The biological regulatory activities of Flammulina velutipes polysaccharide in mice intestinal microbiota, immune repertoire and heart transcriptome

Y Hao, X Liao, X Wang, S Lao, W Liao - International Journal of Biological …, 2021 - Elsevier
The effects of a novel Flammulina velutipes polysaccharide (FVP) on intestinal microbiota,
immune repertoire and heart transcriptome were investigated in this study. The results …

[HTML][HTML] Study on the Efficacy and Mechanism of Lycium barbarum Polysaccharide against Lead-Induced Renal Injury in Mice

W Xie, YY Huang, HG Chen, X Zhou - Nutrients, 2021 - mdpi.com
Lead is one of the most common heavy metal pollutants in the environment. Prolonged
exposure to lead will induce oxidative stress, inflammation, and apoptosis in the kidneys …

Flammulina velutipes polysaccharide improves C57BL/6 mice gut health through regulation of intestine microbial metabolic activity

Y Hao, X Wang, S Yuan, Y Wang, X Liao… - International journal of …, 2021 - Elsevier
Flammulina velutipes polysaccharides (FVP) can improve gut health through gut microbiota
and metabolism regulation. In this study, the 28-days fed experiment was used to investigate …

Sagittaria sagittifolia polysaccharide protects against six-heavy-metal-induced hepatic injury associated with the activation of Nrf2 pathway to regulate oxidative stress …

H Liu, M Zhou, X Zhang, Y Li, J Kong, X Gao… - Journal of Inorganic …, 2022 - Elsevier
The hepatic protective role of Sagittaria sagittifolia polysaccharide (SSP) and its possible
mechanism were discussed in mice and L02 hepatocytes injured by heavy metals mixture of …

Protective effects of Emblica officinalis polysaccharide against lead induced liver injury in mice model

Y Wang, Y Wu, M Xu, MFA Kulyar, M Iqbal, J Wu… - International Journal of …, 2023 - Elsevier
Heavy metal contamination especially lead (Pb) causes a serious threat to global public
health. In the current study, we explored the protective and regulating effects of Emblica …