Recovery of the brain after intraventricular hemorrhage

B Cheng, P Ballabh - Seminars in Fetal and Neonatal Medicine, 2022 - Elsevier
Intraventricular hemorrhage (IVH) remains a major complication of prematurity, worldwide.
The severity of IVH is variable, ranging from a tiny germinal matrix bleed to a moderate-to …

Intraventricular hemorrhage and white matter injury in preclinical and clinical studies

O Romantsik, M Bruschettini, D Ley - Neoreviews, 2019 - publications.aap.org
Germinal matrix–intraventricular hemorrhage (IVH) occurs in nearly half of infants born at
less than 26 weeks' gestation. Up to 50% of survivors with IVH develop cerebral palsy …

Emerging therapies for brain recovery after IVH in neonates: cord blood derived mesenchymal stem cells (MSC) and unrestricted somatic stem cells (USSC)

G Vinukonda, EF La Gamma - Seminars in Perinatology, 2022 - Elsevier
In this report, we summarize evidence on mechanisms of injury after intraventricular
hemorrhage resulting in post-hemorrhagic white matter injury and hydrocephalus and …

Intraventricular hemorrhage: the role of blood components in secondary injury and hydrocephalus

T Garton, RF Keep, DA Wilkinson, JM Strahle… - Translational stroke …, 2016 - Springer
Intraventricular hemorrhage (IVH) is characterized by an influx of blood into the ventricles of
the brain. It has a highly morbid prognosis and develops in more than 12,000 premature …

White matter injury in infants with intraventricular haemorrhage: mechanisms and therapies

P Ballabh, LS de Vries - Nature Reviews Neurology, 2021 - nature.com
Intraventricular haemorrhage (IVH) continues to be a major complication of prematurity that
can result in cerebral palsy and cognitive impairment in survivors. No optimal therapy exists …

Intraventricular haemorrhage and posthaemorrhagic hydrocephalus: pathogenesis, prevention and future interventions

A Whitelaw - Seminars in neonatology, 2001 - Elsevier
Intraventricular haemorrhage (IVH) is still a major complication of preterm birth with serious
disability resulting. The fragile blood vessels in the germinal matrix below the ventricular …

Preterm intraventricular hemorrhage/posthemorrhagic hydrocephalus

TE Inder, JM Perlman, JJ Volpe - Volpe's Neurology of the Newborn, 2025 - Elsevier
Germinal matrix–intraventricular hemorrhage (GMH-IVH) is the most common variety of
neonatal intracranial hemorrhage and is characteristic of the premature infant. This form of …

Cerebral gray matter injuries in infants with intraventricular hemorrhage

DR Sharma, A Agyemang, P Ballabh - Seminars in perinatology, 2022 - Elsevier
While intraventricular hemorrhage (IVH) predominantly damages the periventricular white
matter, it induces substantial injury to the cerebral gray matter. IVH destroys the germinal …

Posthemorrhagic hydrocephalus and brain injury in the preterm infant: dilemmas in diagnosis and management

AJ du Plessis - Seminars in Pediatric Neurology, 1998 - Elsevier
Advances in neonatal critical care have reduced the incidence of intraventricular
hemorrhage (IVH) in the newborn. Paradoxically, however, the prevalence of the …

The pathogenesis of neonatal post‐hemorrhagic hydrocephalus

S Cherian, A Whitelaw, M Thoresen, S Love - Brain Pathology, 2004 - Wiley Online Library
Hydrocephalus after intraventricular hemorrhage (IVH) has emerged as a major
complication of preterm birth and is especially problematic to treat. The hydrocephalus is …