Neural substrates and circuits of drug addiction

MW Feltenstein, RE See… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Drug addiction is a chronic relapsing disorder, and a significant amount of research has
been devoted to understand the factors that contribute to the development, loss of control …

Systems level neuroplasticity in drug addiction

MW Feltenstein, RE See - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Drug addiction is a chronic relapsing disorder for which research has been dedicated to
understand the various factors that contribute to development, loss of control, and …

The neurocircuitry of addiction: an overview

MW Feltenstein, RE See - British journal of pharmacology, 2008 - Wiley Online Library
Drug addiction presents as a chronic relapsing disorder characterized by persistent drug‐
seeking and drug‐taking behaviours. Given the significant detrimental effects of this disease …

Plasticity of addiction: a mesolimbic dopamine short-circuit?

JL Niehaus, ND Cruz-Bermúdez… - American Journal on …, 2009 - Taylor & Francis
The development of drug addiction progresses along a continuum from acute drug use to
compulsive use and drug seeking behavior. Many researchers have focused on identifying …

Addiction and the brain: the role of neurotransmitters in the cause and treatment of drug dependence

DM Tomkins, EM Sellers - Cmaj, 2001 - Can Med Assoc
RECENT SCIENTIFIC ADVANCES HAVE LED to a greater understanding of the
neurobiological processes that underlie drug abuse and addiction. These suggest that …

Neurobiologic processes in drug reward and addiction

B Adinoff - Harvard review of psychiatry, 2004 - Taylor & Francis
Neurophysiologic processes underlie the uncontrolled, compulsive behaviors defining the
addicted state. These “hard-wired” changes in the brain are considered critical for the …

A behavioral/systems approach to the neuroscience of drug addiction

FJ White - Journal of Neuroscience, 2002 - Soc Neuroscience
Drug addiction is likely to affect all of our lives, with any luck not through our own actions but
probably because of one or more of our family and friends. Now firmly entrenched as a brain …

Drug addiction: an affective-cognitive disorder in need of a cure

L Fattore, M Diana - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Drug addiction is a compulsive behavioral abnormality. In spite of pharmacological
treatments and psychosocial support to reduce or eliminate drug intake, addiction tends to …

Neurobiological mechanisms in the transition from drug use to drug dependence

GF Koob, SH Ahmed, B Boutrel, SA Chen… - Neuroscience & …, 2004 - Elsevier
Drug addiction is a chronic relapsing disorder characterized by compulsive drug intake, loss
of control over intake, and impairment in social and occupational function. Animal models …

Drug addiction: updating actions to habits to compulsions ten years on

BJ Everitt, TW Robbins - Annual review of psychology, 2016 - annualreviews.org
A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …