The study of cell reaction to micro and nanotopography is dependent on the method of
manufacture available. Several methods of manufacture have been developed: polymer …

Organised nanotopography mimicking the natural extracellular matrix can be used to control
morphology, cell motility, and differentiation. However, it is still unknown how specific cell …

Coating the surfaces of titanium-based implants with appropriate hierarchical micro/nano-
topographies resembling the structure of natural bone significantly enhances their biological …

Cellular behavior can be influenced by the chemical and physical surface characteristics of
biomedical substrates. To understand the relationships between various topographical …

The development of scaffolds for use in tissue engineering applications requires careful
choice of macroscale properties, such as mechanical characteristics, porosity and …

The interaction of mammalian cells with nanoscale topography has proven to be an
important signaling modality in controlling cell function. Naturally occurring nanotopographic …

Nanotopographical cues of bone implant surface has direct influences on various cell types
during the establishment of osseointegration, a prerequisite of implant bear-loading. Given …

It is thought that by understanding how cells respond to topography, that better tissue
engineering may be achievable. An important consideration in the cellular environment is …

Adult stem cells hold great promise as a source of diverse terminally differentiated cell types
for tissue engineering applications. However, due to the complexity of chemical and …

Available, easy and fast fabrication methods of nanostructured surfaces, and the knowledge
that cells in vivo interacts with nanometer-sized structures/objects, led us to study the impact …