[HTML][HTML] Dual antiplatelet or dual antithrombotic therapy for secondary prevention in high-risk patients with stable coronary artery disease?

W Sumaya, T Geisler, SD Kristensen… - Thrombosis and …, 2019 - thieme-connect.com
Antithrombotic treatment is a key component of secondary prevention following acute
coronary syndromes (ACS). Although dual antiplatelet therapy is standard therapy post …

Is there a need for “triple therapy”? Role of anticoagulation with dual antiplatelet therapy in acute coronary syndromes (ATLAS study & TRAP study)

WL Patrick, C Patel, R Guddeti, A Narayan… - Current cardiology …, 2013 - Springer
In the past two decades there has been a succession of advances in the development of
anticoagulant and antiplatelet therapies to be used in the treatment of ACS. Despite optimal …

Antithrombotic strategy in secondary prevention for high-risk patients with previous acute coronary syndrome: overlap between the PEGASUS eligibility and the …

M Millesimo, E Elia, G Marengo, O De Filippo… - American Journal of …, 2023 - Springer
Background Patients with previous acute coronary syndrome (ACS) are at high risk of
recurrent adverse cardiovascular events. Recently, prolonged dual antiplatelet therapy …

More, more, more: reducing thrombosis in acute coronary syndromes beyond dual antiplatelet therapy—current data and future directions

N Spinthakis, M Farag, B Rocca… - Journal of the American …, 2018 - Am Heart Assoc
Common to the pathogenesis of acute coronary syndromes (ACS) is the formation of arterial
thrombus, which results from platelet activation and triggering of the coagulation cascade. 1 …

Dual antiplatelet therapy in patients at high bleeding risk: less is more—more or less

D Capodanno, A Greco - European Heart Journal, 2023 - academic.oup.com
Risk-based antithrombotic strategies after percutaneous coronary intervention (PCI). Dual
antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is indicated for …

Antithrombotic agents for secondary prevention after acute coronary syndromes: A systematic review and network meta-analysis

AC Fanaroff, V Hasselblad, MT Roe, DL Bhatt… - International Journal of …, 2017 - Elsevier
Background Nine oral antithrombotic medications currently available in the United States
and Europe have been studied in clinical trials for secondary prevention of cardiac events …

[HTML][HTML] Challenges of long-term dual antiplatelet therapy use following acute coronary syndromes

MS Sidhu, R Lyubarova, S Bangalore, MP Bonaca - American heart journal, 2022 - Elsevier
An acute coronary syndrome (ACS) event is associated with a high risk of recurrent ACS,
stroke, and death. To ameliorate the risk of subsequent events, current guidelines for ST …

Use of dual antiplatelet therapy and patient outcomes in those undergoing percutaneous coronary intervention: the ROCKET AF trial

MW Sherwood, DD Cyr, WS Jones, RC Becker… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The authors assessed the use of dual antiplatelet therapy (DAPT) and outcomes
in patients undergoing percutaneous coronary intervention (PCI) during the ROCKET AF …

Dual antiplatelet therapy in coronary artery disease: from the past to the future prospective

A Mangieri, F Gallo, A Sticchi, AA Khokhar… - Cardiovascular …, 2020 - Springer
Antiplatelet therapy, the cornerstone of post coronary stenting antithrombotic therapy,
reduces the rate of hard clinical endpoints in patients treated both conservatively and …

Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind …

EM Ohman, MT Roe, PG Steg, SK James, TJ Povsic… - The Lancet, 2017 - thelancet.com
Background Dual antiplatelet therapy (DAPT), aspirin plus a P2Y12 inhibitor, is the standard
antithrombotic treatment following acute coronary syndromes. The factor Xa inhibitor …