Molecular, population, and clinical aspects of lipoprotein (a): a bridge too far?

NC Ward, KM Kostner, DR Sullivan, P Nestel… - Journal of clinical …, 2019 - mdpi.com
There is now significant evidence to support an independent causal role for lipoprotein
(a)(Lp (a)) as a risk factor for atherosclerotic cardiovascular disease. Plasma Lp (a) …

[HTML][HTML] Lipoprotein (a), Interleukin-6 inhibitors, and atherosclerotic cardiovascular disease: Is there an association?

A Makris, F Barkas, PP Sfikakis, E Liberopoulos… - Atherosclerosis …, 2023 - Elsevier
Background and aims Lipoprotein (a)[Lp (a)] and interleuking-6 (IL-6), an inflammation
biomarker, have been established as distinct targets of the residual atherosclerotic …

Lipoprotein (a) an elusive cardiovascular risk factor

L Berglund, R Ramakrishnan - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Lipoprotein (a)[Lp (a)], is present only in humans, Old World nonhuman primates, and the
European hedgehog. Lp (a) has many properties in common with low-density lipoprotein …

Lipoprotein (a): A missing culprit in the management of athero‐thrombosis?

G Ferretti, T Bacchetti, TP Johnston… - Journal of Cellular …, 2018 - Wiley Online Library
Lipoprotein (a) Lp (a) is a cholesterol‐rich, LDL‐like particle that is independently
associated with an increased risk for ischemic heart disease, atherosclerosis, thrombosis …

Lp (a)(lipoprotein [a]) concentrations and incident atherosclerotic cardiovascular disease: new insights from a large national biobank

AP Patel, M Wang, JP Pirruccello… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Lp (a)(lipoprotein [a]) concentrations are associated with atherosclerotic
cardiovascular disease (ASCVD), and new therapies that enable potent and specific …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies

A Cesaro, A Schiavo, E Moscarella… - Journal of …, 2021 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is an established cardiovascular risk factor, and growing
evidence indicates its causal association with atherosclerotic disease because of the …

Lipoprotein (a), inflammation, and atherosclerosis

SA Di Fusco, AP Maggioni, P Scicchitano… - Journal of clinical …, 2023 - mdpi.com
Growing evidence has shown that high levels of lipoprotein (a)(Lp (a)) and chronic
inflammation may be responsible for the residual risk of cardiovascular events in patients …

Lipoprotein (a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop …

S Tsimikas, JL Hall - Journal of the American College of Cardiology, 2012 - jacc.org
Recent published studies have provided increasing evidence that lipoprotein (a)[Lp (a)] may
be a potential causal, genetic, independent risk factor for cardiovascular disease (CVD). Lp …

Looking at Lp (a) and related cardiovascular risk: from scientific evidence and clinical practice

TM Stulnig, C Morozzi, R Reindl-Schwaighofer… - Current Atherosclerosis …, 2019 - Springer
Purpose of Review A considerable body of data from genetic and epidemiological studies
strongly support a causal relationship between high lipoprotein (a)[Lp (a)] levels, and the …