Lipoprotein (a)–An independent causal risk factor for cardiovascular disease and current therapeutic options

U Kassner, T Schlabs, A Rosada… - Atherosclerosis …, 2015 - Elsevier
It is widely accepted that elevated levels of lipoprotein (a)(Lp (a)) are associated with an
increased risk for cardiovascular diseases. Several studies have identified Lp (a) as …

[HTML][HTML] Lipoprotein (a) measurement issues: are we making a mountain out of a molehill?

F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] became besides LDL cholesterol one of the most attractive
targets for intervention in cardiovascular disease. Strong genetic evidence supports the …

Plasma lipoprotein Lp (a), markers of haemostasis and inflammation, and risk and severity of coronary heart disease

A Imhof, D Rothenbacher… - European Journal of …, 2003 - academic.oup.com
Background Elevated plasma (Lp (a)) levels may represent an independent risk factor for
atherothrombotic complications but the relation between Lp (a) levels and the extent of …

[PDF][PDF] Lipoprotein (a)

F Kronenberg - … and treatment of atherosclerosis: improving state …, 2021 - library.oapen.org
Abstract Lipoprotein (a)[Lp (a)] is an atherogenic lipoprotein with a strong genetic regulation.
Up to 90% of the concentrations are explained by a single gene, the LPA gene. The …

Consensus document on Lipoprotein (a) from the Italian Society for the Study of Atherosclerosis (SISA)

G Chiesa, MG Zenti, A Baragetti, CM Barbagallo… - Nutrition, Metabolism …, 2023 - Elsevier
Aims In view of the consolidating evidence on the causal role of Lp (a) in cardiovascular
disease, the Italian Society for the Study of Atherosclerosis (SISA) has assembled a …

Lipoprotein (a) as a risk factor for ischemic heart disease: metaanalysis of prospective studies

WY Craig, LM Neveux, GE Palomaki… - Clinical …, 1998 - academic.oup.com
Although in vitro studies support a pathophysiologic role for lipoprotein (a)[Lp (a)] in the
development of atherosclerosis, and retrospective studies consistently report that there is a …

Screening and therapeutic management of lipoprotein (a) excess: review of the epidemiological evidence, guidelines and recommendations

G Lippi, M Franchini, G Targher - Clinica Chimica Acta, 2011 - Elsevier
Lipoprotein (a)(Lp (a)) is a low density lipoprotein-like particle in which apolipoprotein B100
is covalently linked to the unique apolipoprotein (a). There is a mounting body of evidence …

[HTML][HTML] Oxidized phospholipids and lipoprotein-associated phospholipase A2 as important determinants of Lp (a) functionality and pathophysiological role

AD Tselepis - Journal of Biomedical Research, 2018 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)[Lp (a)] is composed of a low density lipoprotein (LDL)-like particle to
which apolipoprotein (a)[apo (a)] is linked by a single disulfide bridge. Lp (a) is considered a …

Lipoprotein (a) concentration and apolipoprotein (a) size: a synergistic role in advanced atherosclerosis?

SM Marcovina, ML Koschinsky - Circulation, 1999 - Am Heart Assoc
Despite more than 3 decades of intense scientific research that has fostered our
understanding of the structure and biochemistry of lipoprotein (a)[Lp (a)], the …

Lipoprotein (a)-cholesterol and coronary heart disease in the Framingham Heart Study

LJ Seman, C DeLuca, JL Jenner, LA Cupples… - Clinical …, 1999 - academic.oup.com
Background: Increased plasma lipoprotein (a)[Lp (a)] concentrations have been reported to
be an independent risk factor for coronary heart disease (CHD) in some prospective studies …