Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …

Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …

The aging process is driven by interrelated mechanisms that lead to the emergence of
characteristic phenotypes that include changes in body composition, energy production and …

The rate of biological aging is modulated in part by genes interacting with stressor
exposures. Basic research has shown that exposure to short-term stress can strengthen …

Gerontology has made considerable progress in the understanding of the mechanisms
underlying the ageing process and age-related neurodegenerative disorders. However …

Psychosocial stress—especially when chronic, excessive, or occurring early in life—has
been associated with accelerated aging and increased disease risk. With rapid aging of the …

The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Geroscience offers a counterpoint to the challenged pursuit of curing diseases of aging, by
focusing on slowing the biological aging process for extended healthspan earlier in life …

Ageing is driven by the inexorable and stochastic accumulation of damage in biomolecules
vital for proper cellular function. Although this process is fundamentally haphazard and …

Chronic stress has been shown to promote numerous aging-related diseases, and to
accelerate the aging process itself. Of particular interest is the impact of stress on …