In eukaryotes, RNA polymerase (RNAP) III transcribes hundreds of genes for tRNAs and 5S
rRNA, among others, which share similar promoters and stable transcription initiation …

RNA synthesis in eukaryotes is divided among three RNA polymerases (RNAPs). RNAP III
transcribes hundreds of tRNA genes and fewer additional short RNA genes. We survey …

Abstract RNA polymerase II (RNAPII)‐mediated gene transcription initiates at promoters and
ends at terminators. Transcription termination is intimately connected to 3′‐end processing …

The highly abundant, small stable RNAs that are synthesized by RNA polymerase III
(RNAPIII) have key functional roles, particularly in the protein synthesis apparatus. Their …

Precise regulation of transcription by RNA polymerase II (RNAPII) is critical for organismal
growth and development. However, what determines whether an engaged RNAPII will …

Understanding the mechanism of transcription termination by a eukaryotic RNA polymerase
(RNAP) has been limited by lack of a characterizable intermediate that reflects transition …

RNA polymerase III catalyses the synthesis of tRNAs in eukaryotic organisms. Through
combined biochemical and structural characterisation, multiple auxiliary factors have been …

Coordination of transcription and processing of RNA is a basic principle in regulation of
gene expression in eukaryotes. In the case of mRNA, coordination is primarily founded on a …

The cycle of eukaryotic transcription, from initiation to elongation and termination is
regulated at multiple steps. Coordinated action of regulatory factors keeps in check the …

Metazoan gene expression is often regulated after the recruitment of RNA polymerase II (Pol
II) to promoters, through the controlled release of promoter-proximally paused Pol II into …