The magnitude and scope of intrinsic age-correlated and host endocrine age-correlated
gene expression in breast cancer is not well understood. From age-correlated gene …

To explore the hypothesis that aging not only increases breast cancer incidence but also
alters breast cancer biology, we correlated patient age at diagnosis with tumor histology …

Introduction Age is one of the most important risk factors for human malignancies, including
breast cancer; in addition, age at diagnosis has been shown to be an independent indicator …

Background: Age is the strongest breast cancer risk factor, with overall breast cancer risk
increasing steadily beginning at approximately 30 years of age. However, while breast …

Breast cancer is a heterogeneous malignancy; its age-specific incidence profile rises
exponentially until menopause and increases more slowly thereafter, reflecting the …

Background: Breast cancer developed at a young age (≤ 45 years) is hypothesized to have
unique biology; however, findings in this field are controversial. Methods: We compared the …

Background Aging is a comorbidity of breast cancer suggesting that aging-associated
transcriptome changes may promote breast cancer progression. However, the mechanism …

Purpose Breast cancer arising in young women is correlated with inferior survival and higher
incidence of negative clinicopathologic features. The biology driving this aggressive disease …

522 Background: Breast cancer in young women [YW] has a poorer prognosis, is less likely
hormone sensitive, and has yet to be defined as a unique biologic phenotype. The …

Editorial Langevin, Pinney, Leung & Ho a cytosine in a gene promoter may not exert an
obvious effect on gene expression, the random accumulation (or loss) of several such marks …