Reflections on modeling poliovirus transmission and the polio eradication endgame

KM Thompson, DA Kalkowska - Risk Analysis, 2021 - Wiley Online Library
Abstract The Global Polio Eradication Initiative (GPEI) partners engaged modelers during
the past nearly 20 years to support strategy and policy discussions and decisions, and to …

Coordinated global cessation of oral poliovirus vaccine use: Options and potential consequences

DA Kalkowska, SGF Wassilak, E Wiesen… - Risk …, 2024 - Wiley Online Library
Due to the very low, but nonzero, paralysis risks associated with the use of oral poliovirus
vaccine (OPV), eradicating poliomyelitis requires ending all OPV use globally. The Global …

Review of poliovirus modeling performed from 2000 to 2019 to support global polio eradication

KM Thompson, DA Kalkowska - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Over the last 20 years (2000-2019) the partners of the Global Polio Eradication
Initiative (GPEI) invested in the development and application of mathematical models of …

Polio endgame risks and the possibility of restarting the use of oral poliovirus vaccine

RJ Duintjer Tebbens, KM Thompson - Expert Review of Vaccines, 2018 - Taylor & Francis
Introduction: Ending all cases of poliomyelitis requires successful cessation of all oral
poliovirus vaccine (OPV), but the Global Polio Eradication Initiative (GPEI) partners should …

[HTML][HTML] Looking back at prospective modeling of outbreak response strategies for managing global type 2 oral poliovirus vaccine (OPV2) cessation

KM Thompson, DA Kalkowska… - Frontiers in Public …, 2023 - frontiersin.org
Introduction Detection of poliovirus transmission and ongoing oral poliovirus vaccine (OPV)
use continue to delay poliomyelitis eradication. In 2016, the Global Polio Eradication …

Expected implications of globally coordinated cessation of serotype 3 oral poliovirus vaccine (OPV) before serotype 1 OPV

DA Kalkowska, KM Thompson - Risk Analysis, 2021 - Wiley Online Library
Globally coordinated cessation of all three serotypes of oral poliovirus vaccine (OPV)
represents a critical part of a successful polio endgame, which the Global Polio Eradication …

Global transmission of live polioviruses: updated dynamic modeling of the polio endgame

DA Kalkowska, MA Pallansch, SGF Wassilak… - Risk …, 2021 - Wiley Online Library
Nearly 20 years after the year 2000 target for global wild poliovirus (WPV) eradication, live
polioviruses continue to circulate with all three serotypes posing challenges for the polio …

Polio eradicators use integrated analytical models to make better decisions

KM Thompson, RJ Duintjer Tebbens… - …, 2015 - pubsonline.informs.org
Achieving global polio eradication requires that global stakeholders coordinate and
cooperate to invest human and financial resources in interventions that prevent virus …

Updated characterization of post‐OPV cessation risks: Lessons from 2019 serotype 2 outbreaks and implications for the probability of OPV restart

DA Kalkowska, MA Pallansch, SL Cochi… - Risk …, 2021 - Wiley Online Library
After the globally coordinated cessation of any serotype of oral poliovirus vaccine (OPV),
some risks remain from undetected, existing homotypic OPV‐related transmission and/or …

[HTML][HTML] Assessing the stability of polio eradication after the withdrawal of oral polio vaccine

M Famulare, C Selinger, KA McCarthy, PA Eckhoff… - PLoS …, 2018 - journals.plos.org
The oral polio vaccine (OPV) contains live-attenuated polioviruses that induce immunity by
causing low virulence infections in vaccine recipients and their close contacts. Widespread …