Calcium is an important early signal in wound healing, yet how these early signals promote
regeneration remains unclear. Peptidylarginine deiminases (PADs), a family of calcium …

Spinal cord regenerative ability is lost with development, but the mechanisms underlying this
loss are still poorly understood. In chick embryos, effective regeneration does not occur after …

PADs (peptidylarginine deiminases) are calcium-dependent enzymes that change protein-
bound arginine to citrulline (citrullination/deimination) affecting protein conformation and …

Tissue injury can lead to scar formation or tissue regeneration. How regenerative animals
sense initial tissue injury and transform wound signals into regenerative growth is an …

Peptidylarginine deiminases (PADs) are calcium dependent enzymes with physiological
and pathophysiological roles conserved throughout phylogeny. PADs promote post …

Peptidylarginine deiminases (PADs) are calcium-dependent enzymes that mediate
citrullination, an irreversible post-translational modification (PTM). PAD enzymes have …

In humans, skin is the largest organ and serves as a barrier between our body and the
outside world. Skin protects our internal organs from external pathogens and other …

Matrilin-1 is the prototypical member of the matrilin protein family and is highly expressed in
cartilage. However, gene targeting of matrilin-1 in mouse did not lead to pronounced …

Peptidyl arginine deiminase (PAD) 4 is a nuclear enzyme that catalyzes the posttranslational
conversion of arginine residues to citrulline. Posttranslational protein citrullination has been …

Alligators are crocodilians and among few species that endured the Cretaceous–Paleogene
extinction event. With long life spans, low metabolic rates, unusual immunological …