Epigenetics in kidney diseases

H Ding, L Zhang, Q Yang, X Zhang, X Li - Advances in clinical chemistry, 2021 - Elsevier
Epigenetics examines heritable changes in DNA and its associated proteins except
mutations in gene sequence. Epigenetic regulation plays fundamental roles in kidney cell …

[HTML][HTML] Beyond genetics: epigenetic code in chronic kidney disease

RS Dwivedi, JG Herman, TA McCaffrey, DSC Raj - Kidney international, 2011 - Elsevier
Epigenetics refers to a heritable change in the pattern of gene expression that is mediated
by a mechanism specifically not due to alterations in the primary nucleotide sequence. Well …

Investigation of epigenetics in kidney cell biology

LX Li, E Agborbesong, L Zhang, X Li - Methods in cell biology, 2019 - Elsevier
Epigenetics is the study of heritable changes in DNA or its associated proteins except
mutations in gene sequence. Epigenetic regulation plays fundamental roles in the …

Epigenetics of kidney disease

N Wanner, W Bechtel-Walz - Cell and tissue research, 2017 - Springer
DNA methylation and histone modifications determine renal programming and the
development and progression of renal disease. The identification of the way in which the …

Epigenetics of progression of chronic kidney disease: fact or fantasy?

MR Wing, A Ramezani, HS Gill, JM Devaney… - Seminars in …, 2013 - Elsevier
Epigenetic modifications are important in the normal functioning of the cell, from regulating
dynamic expression of essential genes and associated proteins to repressing those that are …

[HTML][HTML] Recent developments in epigenetics of acute and chronic kidney diseases

MA Reddy, R Natarajan - Kidney international, 2015 - Elsevier
The growing epidemic of obesity and diabetes, the aging population as well as prevalence
of drug abuse has led to significant increases in the rates of the closely associated acute …

New insights into molecular mechanisms of epigenetic regulation in kidney disease

I Mimura, T Tanaka, M Nangaku - Clinical and Experimental …, 2016 - Wiley Online Library
The number of patients with kidney failure has increased in recent years. Different factors
contribute to the progression of chronic kidney disease, including glomerular sclerosis …

The epigenetic conductor: a genomic orchestrator in chronic kidney disease complications?

TJ Ekström, P Stenvinkel - Journal of nephrology, 2009 - europepmc.org
Epigenetics defines the cellularly heritable properties of genome function, which are not
directly encoded in the DNA primary sequence. The underlying mechanisms orchestrate cell …

Noncoding RNA and epigenetic gene regulation in renal diseases

SK Kota, SB Kota - Drug Discovery Today, 2017 - Elsevier
Highlights•miRNAs and long non-coding RNAs are differentially expressed in renal
diseases.•Chromatin modifying proteins are important gene regulators in renal …

Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease?

YA Ko, K Susztak - Seminars in nephrology, 2013 - Elsevier
Epigenetics refers to functionally relevant modifications of the genome that do not involve a
change in the nucleotide sequence. Examples of such modifications are DNA methylation …