Methylenetetrahydrofolate reductase gene polymorphisms are not associated with embryo chromosomal abnormalities and IVF outcomes

R Morales, B Lledó, JA Ortiz, A Cascales… - Systems Biology in …, 2021 - Taylor & Francis
The aim of our study was to investigate the effect of maternal and embryo MTHFR C677T
and A1298C polymorphisms on embryo aneuploidies and mosaicism and the correlation …

Methylenetetrahydrofolate reductase C677T and A1298C variants do not affect ongoing pregnancy rates following IVF

AT Dobson, RM Davis, MP Rosen, S Shen… - Human …, 2007 - academic.oup.com
BACKGROUND: There is concern that IVF could compromise normal imprinting and
methylation of DNA. Methylenetetrahydrofolate reductase (MTHFR) regulates the flow of folic …

Association between maternal MTHFR C677T/A1298C combination polymorphisms and IVF/ICSI outcomes: a retrospective cohort study

YJ Lu, Q Li, LX Chen, T Tian, J Kang… - Human …, 2023 - academic.oup.com
STUDY QUESTION What are the roles of maternal 5, 10-methylenetetrahydrofolate
reductase (MTHFR) C677T/A1298C combination polymorphisms on the embryological and …

[HTML][HTML] Prevalent genotypes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) in spontaneously aborted embryos

J Bae, SJ Shin, SH Cha, DH Choi, S Lee, NK Kim - Fertility and sterility, 2007 - Elsevier
OBJECTIVE: To assess prevalent 5, 10-methylenetetrahydrofolate reductase (MTHFR)
polymorphisms in spontaneously aborted embryos. DESIGN: A retrospectively analyzed …

Prevalent genotypes of methylenetetrahydrofolate reductase (MTHFR) in recurrent miscarriage and recurrent implantation failure

Y Zhu, T Wu, L Ye, G Li, Y Zeng, Y Zhang - Journal of Assisted …, 2018 - Springer
Objective To evaluate the association of two common methylenetetrahydrofolate reductase
(MTHFR) gene polymorphisms with recurrent miscarriage (RM) and repeated implantation …

Methylenetetrahydrofolate reductase polymorphisms and pregnancy outcome

M Turgal, F Gumruk, E Karaagaoglu… - Geburtshilfe und …, 2018 - thieme-connect.com
Introduction Aim of the study was to evaluate the effect of methylenetetrahydrofolate
reductase (MTHFR) polymorphisms on pregnancy outcome. Materials and Methods A total …

Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy

M Enciso, J Sarasa, L Xanthopoulou, S Bristow… - Human genetics, 2016 - Springer
MTHFR is an important enzyme in the metabolism of folic acid and is crucial for reproductive
function. Variation in the sequence of MTHFR has been implicated in subfertility, but …

Methylenetetrahydrofolate Reductase (MTHFR) genetic polymorphisms and the risk of infertility in couples accessing Assisted Reproductive technologies: a …

C Ledowsky, A Steel, J Schloss - Advances in Integrative Medicine, 2021 - Elsevier
Objectives The aim of this literature review is to examine the relationship between
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and assisted reproductive …

[PDF][PDF] Association of Methylenetetrahydrofolate Reductase Gene Polymorphism C677T with Oocyte Number and Embryo Quality in Iraqi Infertile Women Undergoing …

RZ Al-Yasiry, MA Jawad, MS Abbood - Al-Rafidain Journal of Medical …, 2024 - iasj.net
Abstract Background: Methylenetetrahydrofolate reductase (MTHFR) C677T is a single
nucleotide polymorphism (SNP) that affects the production of 5-methyltetrahydrofolate (5 …

Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms resulting in suboptimal oocyte maturation: a discussion of folate status, neural tube defects …

PH Jongbloet, ALM Verbeek, M Den Heijer… - Journal of Experimental …, 2008 - Springer
Several conditions apparent at birth, eg, neural tube defects (NTDs) and cardiac anomalies,
are associated with polymorphisms in folate-related genes, such as the 677C→ T …