Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …
Defining a therapeutic target for pallidal deep brain stimulation for dystonia
T Cheung, AM Noecker, RL Alterman… - Annals of …, 2014 - Wiley Online Library
Objective To create a data‐driven computational model that identifies brain regions most
frequently influenced by successful deep brain stimulation (DBS) of the globus pallidus (GP) …
frequently influenced by successful deep brain stimulation (DBS) of the globus pallidus (GP) …
Functional and structural connectivity patterns associated with clinical outcomes in deep brain stimulation of the globus pallidus internus for generalized dystonia
BACKGROUND AND PURPOSE: Deep brain stimulation is a well-established treatment for
generalized dystonia, but outcomes remain variable. Establishment of an imaging marker to …
generalized dystonia, but outcomes remain variable. Establishment of an imaging marker to …
Probabilistic mapping of the antidystonic effect of pallidal neurostimulation: a multicentre imaging study
Deep brain stimulation of the internal globus pallidus is a highly effective and established
therapy for primary generalized and cervical dystonia, but therapeutic success is …
therapy for primary generalized and cervical dystonia, but therapeutic success is …
A localized pallidal physiomarker in cervical dystonia
WJ Neumann, A Horn, S Ewert, J Huebl… - Annals of …, 2017 - Wiley Online Library
Objective Deep brain stimulation (DBS) allows for direct recordings of neuronal activity from
the human basal ganglia. In Parkinson's disease, a disease‐specific physiomarker was …
the human basal ganglia. In Parkinson's disease, a disease‐specific physiomarker was …
Patterns of cortical synchronization in isolated dystonia compared with Parkinson disease
S Miocinovic, C de Hemptinne, S Qasim… - JAMA …, 2015 - jamanetwork.com
Importance Isolated dystonia and Parkinson disease (PD) are disorders of the basal
gangliothalamocortical network. They have largely distinct clinical profiles, but both …
gangliothalamocortical network. They have largely distinct clinical profiles, but both …
Deep brain stimulation in dystonia
Renewed interest in stereotaxy for dystonia followed the introduction of deep brain
stimulation (DBS) in Parkinson's disease and essential tremor in the 1990s. DBS evolved …
stimulation (DBS) in Parkinson's disease and essential tremor in the 1990s. DBS evolved …
Deep brain stimulation for dystonia
M Tagliati, J Shils, C Sun, R Alterman - Expert review of medical …, 2004 - Taylor & Francis
Dystonia is a movement disorder characterized by involuntary muscular contractions that
generate twisting and repetitive movements and/or abnormal postures. It can affect a few …
generate twisting and repetitive movements and/or abnormal postures. It can affect a few …
Meta-regression analysis of the long-term effects of pallidal and subthalamic deep brain stimulation for the treatment of isolated dystonia
YS Wu, LH Ni, RM Fan, MY Yao - World neurosurgery, 2019 - Elsevier
Objective The globus pallidus internus (GPi) and subthalamic nucleus (STN) are therapeutic
targets for deep brain stimulation (DBS) in the treatment of isolated dystonia. We conducted …
targets for deep brain stimulation (DBS) in the treatment of isolated dystonia. We conducted …
Cortico-pallidal oscillatory connectivity in patients with dystonia
Primary dystonia has been associated with an underlying dysfunction of a wide network of
brain regions including the motor cortex, basal ganglia, cerebellum, brainstem and spinal …
brain regions including the motor cortex, basal ganglia, cerebellum, brainstem and spinal …