Mast cells participate in allergy and inflammation by secreting inflammatory mediators such
as histamine and proinflammatory cytokines. Flavonoids are naturally occurring molecules …

Objective and design: Mast cell-mediated allergic inflammation is involved in many diseases
such as asthma, sinusitis, and rheumatoid arthritis. Mast cells induce production of pro …

Mast cells play an important role in the pathogenesis of allergic diseases through the
release of inflammatory mediators such as histamine, cysteinyl leukotrienes, cytokines, and …

Background Flavonoids have a variety of activities including anti‐allergic activities, and are
known to inhibit histamine release from human basophils and murine mast cells. Objective …

1 Mast cells participate in allergies, and also in immunity and inflammation by secreting
proinflammatory cytokines. 2 Flavonoids are naturally occurring polyphenolic plant …

Background: Activation of mast cells and basophils through allergen stimulation releases
chemical mediators and synthesizes cytokines. Among these cytokines, IL-4, IL-13, and IL-5 …

Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and
autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and …

The anti-allergic activities of polyphenol fractions extracted from immature fruits of apple
(Rosaceae, Malus sp.) were evaluated by in vitro assays. A crude apple polyphenol (CAP) …

The discovery of drugs for the treatment of inflammatory allergic diseases such as, asthma,
allergic rhinitis, and sinusitis is a very important subject in human health. Gallic acid (3, 4, 5 …

A great number of people are suffering from allergic inflammatory disease such as asthma,
atopic dermatitis, and sinusitis. Therefore discovery of drugs for the treatment of these …