Association study among candidate genetic polymorphisms and chemotherapy-related severe toxicity in testicular cancer patients
MA Lavanderos, JP Cayún, Á Roco… - Frontiers in …, 2019 - frontiersin.org
Testicular cancer is one of the most commonly occurring malignant tumors in young men
with fourfold higher rate of incidence and threefold higher mortality rates in Chile than the …
with fourfold higher rate of incidence and threefold higher mortality rates in Chile than the …
Current insights into interethnic variability in testicular cancers: population pharmacogenetics, clinical trials, genetic basis of chemotherapy-induced toxicities and …
A Vasistha, R Kothari, A Mishra… - Current topics in …, 2020 - ingentaconnect.com
Testicular cancer is an aggressive malignancy with a rising incidence rate across the globe.
Testicular germ cell tumors are the most commonly diagnosed cancers, and surgical …
Testicular germ cell tumors are the most commonly diagnosed cancers, and surgical …
Outcome Definition Influences the Relationship between Genetic Polymorphisms of ERCC1, ERCC2, SLC22A2 and Cisplatin Nephrotoxicity in Adult Testicular …
Z Zazuli, LS Otten, BI Drögemöller, M Medeiros… - Genes, 2019 - mdpi.com
Although previous research identified candidate genetic polymorphisms associated with
cisplatin nephrotoxicity, varying outcome definitions potentially contributed to the variability …
cisplatin nephrotoxicity, varying outcome definitions potentially contributed to the variability …
The role of phase I and II genetic polymorphisms, smoking, alcohol and cancer family history, in the risk of developing testicular cancer
A Roco, A Lavanderos, JP Cayún… - Pharmacogenetics …, 2019 - journals.lww.com
Background Testicular cancer (TCa) is a malignant tumor with highest incidence and
mortality rates in Chile. The genes coding for cytochrome P450, glutathione-S-transferases …
mortality rates in Chile. The genes coding for cytochrome P450, glutathione-S-transferases …
Unusual gastrointestinal and cutaneous toxicities by bleomycin, etoposide, and cisplatin: a case report with pharmacogenetic analysis to personalize treatment
M Del Re, T Latiano, L Fidilio, G Restante, F Morelli… - EPMA Journal, 2017 - Springer
The standard treatment of testicular germ cell tumors is based on the combination of
bleomycin, etoposide, and cisplatin (PEB). However, this treatment may be associated with …
bleomycin, etoposide, and cisplatin (PEB). However, this treatment may be associated with …
Genomic profile in a non-seminoma testicular germ-cell tumor cohort reveals a potential biomarker of sensitivity to platinum-based therapy
R González-Barrios, N Alcaraz, M Montalvo-Casimiro… - Cancers, 2022 - mdpi.com
Simple Summary Despite having a favorable response to platinum-based chemotherapies,~
15% of Testicular Germ-Cell Tumor (TGCT) patients are platinum-resistant. Incidence and …
15% of Testicular Germ-Cell Tumor (TGCT) patients are platinum-resistant. Incidence and …
Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy
LC Steggink, H Boer, C Meijer, JD Lefrandt… - The …, 2021 - nature.com
Genetic variation may mediate the increased risk of cardiovascular disease (CVD) in
chemotherapy-treated testicular cancer (TC) patients compared to the general population …
chemotherapy-treated testicular cancer (TC) patients compared to the general population …
Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and-M1, a retrospective cross …
J Oldenburg, SM Kraggerud, M Brydøy… - Journal of translational …, 2007 - Springer
Background To assess the impact of polymorphisms in Glutathione S-transferase (GST)-P1,-
M1, and-T1 on self-reported chemotherapy-induced long-term toxicities in testicular cancer …
M1, and-T1 on self-reported chemotherapy-induced long-term toxicities in testicular cancer …
ERCC1 rs11615 polymorphism and chemosensitivity to platinum drugs in patients with ovarian cancer: a systematic review and meta-analysis
Y Zhang, S Cao, C Zhuang, J Chen, X Chen… - Journal of Ovarian …, 2021 - Springer
Objective To explore the relationship between ERCC1 rs11615 polymorphism and
chemosensitivity to platinum drugs in ovarian cancer by the method of meta-analysis …
chemosensitivity to platinum drugs in ovarian cancer by the method of meta-analysis …
GSTP1 and ABCB1 Polymorphisms Predicting Toxicities and Clinical Management on Carboplatin and Paclitaxel‐Based Chemotherapy in Ovarian Cancer
AC Ferracini, L Lopes-Aguiar… - Clinical and …, 2021 - Wiley Online Library
Variation in drug disposition genes might contribute to susceptibility to toxicities and
interindividual differences in clinical management on chemotherapy for epithelial ovarian …
interindividual differences in clinical management on chemotherapy for epithelial ovarian …