Redox stress reshapes carbon fluxes of Pseudomonas putida for cytosolic glucose oxidation and NADPH generation
The soil bacterium and metabolic engineering platform Pseudomonas putida tolerates high
levels of endogenous and exogenous oxidative stress, yet the ultimate reason of such …
levels of endogenous and exogenous oxidative stress, yet the ultimate reason of such …
Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress
As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …
Response of Pseudomonas putida KT2440 to increased NADH and ATP demand
Adenosine phosphate and NAD cofactors play a vital role in the operation of cell
metabolism, and their levels and ratios are carefully regulated in tight ranges. Perturbations …
metabolism, and their levels and ratios are carefully regulated in tight ranges. Perturbations …
Multi-omics analysis unravels a segregated metabolic flux network that tunes co-utilization of sugar and aromatic carbons in Pseudomonas putida
Pseudomonas species thrive in different nutritional environments and can catabolize
divergent carbon substrates. These capabilities have important implications for the role of …
divergent carbon substrates. These capabilities have important implications for the role of …
[HTML][HTML] Reserve flux capacity in the pentose phosphate pathway enables Escherichia coli's rapid response to oxidative stress
To counteract oxidative stress and reactive oxygen species (ROS), bacteria evolved various
mechanisms, primarily reducing ROS through antioxidant systems that utilize cofactor …
mechanisms, primarily reducing ROS through antioxidant systems that utilize cofactor …
Metabolic response of Pseudomonas putida to increased NADH regeneration rates
Pseudomonas putida efficiently utilizes many different carbon sources without the formation
of byproducts even under conditions of stress. This implies a high degree of flexibility to …
of byproducts even under conditions of stress. This implies a high degree of flexibility to …
Pseudomonas putida KT2440 is naturally endowed to withstand industrial‐scale stress conditions
A Ankenbauer, RA Schäfer, SC Viegas… - Microbial …, 2020 - Wiley Online Library
Pseudomonas putida is recognized as a very promising strain for industrial application due
to its high redox capacity and frequently observed tolerance towards organic solvents. In this …
to its high redox capacity and frequently observed tolerance towards organic solvents. In this …
Synthetic control of metabolic states in Pseudomonas putida by tuning polyhydroxyalkanoate Cycle
Polyhydroxyalkanoates (PHAs) are polyesters produced by numerous microorganisms for
energy and carbon storage. Simultaneous synthesis and degradation of PHA drives a …
energy and carbon storage. Simultaneous synthesis and degradation of PHA drives a …
[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism
PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …
Aspartate metabolism and pyruvate homeostasis triggered by oxidative stress in Pseudomonas fluorescens: a functional metabolomic study
A Alhasawi, M Leblanc, ND Appanna, C Auger… - Metabolomics, 2015 - Springer
There is mounting evidence that metabolic reprogramming is critical for the survival of
organisms exposed to changing and stressed environments. Using the soil microbe …
organisms exposed to changing and stressed environments. Using the soil microbe …