[HTML][HTML] A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani
Metals have been used in medicine since ancient times for the treatment of different ailments
with various elements such as iron, gold and arsenic. Metal complexes have also been …
with various elements such as iron, gold and arsenic. Metal complexes have also been …
Potentially bioactive organotin (IV) compounds: synthesis, characterization, in vitro bioactivities and interaction with SS-DNA
Fourteen new organotin (IV) complexes with general formula R 2 SnL 2 or R 3 SnL where
R= CH 3, C 2 H 5, C 4 H 9, C 6 H 5, C 6 H 11, CH 2–C 6 H 5, C (CH 3) 3, C 8 H 17 and L= N …
R= CH 3, C 2 H 5, C 4 H 9, C 6 H 5, C 6 H 11, CH 2–C 6 H 5, C (CH 3) 3, C 8 H 17 and L= N …
Organotin (IV) complexes of carboxylate derivative as potential chemotherapeutic agents against Leishmania
HQ Qurrat-ul-Ain, A Nadhman, M Sirajuddin… - Inorganica Chimica …, 2014 - Elsevier
The aim of the present research is to search for new antileishmanial drugs as potential
chemotherapeutic agents. We have some newly synthesized organotin (IV) based peptide …
chemotherapeutic agents. We have some newly synthesized organotin (IV) based peptide …
Organogold (III)-dithiocarbamate compounds and their coordination analogues as anti-tumor and anti-leishmanial metallodrugs
AL de Andrade Querino, AM de Sousa… - Journal of Inorganic …, 2023 - Elsevier
The limited chemical stability of gold (III)-based compounds in physiological environment
has been a challenge in drug discovery, and organometallic chemistry might provide the …
has been a challenge in drug discovery, and organometallic chemistry might provide the …
[HTML][HTML] Synthesis, spectroscopic characterization, antileishmanial, DNA binding, antioxidant, cytotoxicity, antifungal and antibacterial studies of organotin (IV) …
S Hussain, S Shujah, A Rehman, ST Hussain… - Arabian Journal of …, 2023 - Elsevier
Six new organotin (IV) complexes,[Bu 2 SnL](1),[Me 2 SnL](2),[Me 3 SnL](3),[Bu 3
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …
Investigation of the antileishmanial activity and mechanisms of action of acetyl-thiohydantoins
BT da Silva Bortoleti, MD Gonçalves… - Chemico-Biological …, 2022 - Elsevier
The currently available treatment options for leishmaniasis are associated with high costs,
severe side effects, and high toxicity. In previous studies, thiohydantoins demonstrated some …
severe side effects, and high toxicity. In previous studies, thiohydantoins demonstrated some …
From synthesis to bioactivity: Characterization, crystallography, antimalarial and antimicrobial activities of hydrazone-derived organotin (IV) complexes
In the pursuit of therapeutic agents against malarial and microbial infections, a series of
pentacoordinated organotin (IV) complexes [R 2 SnL 1-4] were synthesized through the …
pentacoordinated organotin (IV) complexes [R 2 SnL 1-4] were synthesized through the …
[HTML][HTML] Screening a natural product-based library against kinetoplastid parasites
Kinetoplastid parasites cause vector-borne parasitic diseases including leishmaniasis,
human African trypanosomiasis (HAT) and Chagas disease. These Neglected Tropical …
human African trypanosomiasis (HAT) and Chagas disease. These Neglected Tropical …
[HTML][HTML] Development of Thiophene Compounds as Potent Chemotherapies for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major
F Rodriguez, E Iniguez, G Pena Contreras, H Ahmed… - Molecules, 2018 - mdpi.com
Leishmania major (L. major) is a protozoan parasite that causes cutaneous leishmaniasis.
About 12 million people are currently infected with an annual incidence of 1.3 million cases …
About 12 million people are currently infected with an annual incidence of 1.3 million cases …
[HTML][HTML] Organotin (IV) esters of 4-maleimido-benzoic acid: synthesis, characterization and in vitro anti-leishmanial effects
Six new diorganotin (IV) esters with the general composition R2SnL2 (where R: Me (1), Et
(2), Pr (3), Bu (4), Ph (5), Bz (6) and L (7): pN-maleimido-benzoic acid) have been …
(2), Pr (3), Bu (4), Ph (5), Bz (6) and L (7): pN-maleimido-benzoic acid) have been …