[HTML][HTML] Effects of antidepressant on FKBP51 mRNA expression and neuroendocrine hormones in patients with panic disorder

Z Zou, Y Huang, M Maes, J Wang, Y He, W Min, B Zhou - BMC psychiatry, 2024 - Springer
The purpose of this study was to investigate the effects of escitalopram on the peripheral
expression of hypothalamic-pituitary-adrenal (HPA) axis-related genes (FKBP51, HSP90 …

[HTML][HTML] Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder

J Li, R Li, D Li, J Zhang, X Luo, Y Zhang - Frontiers in Psychiatry, 2023 - frontiersin.org
Background We aimed to explore the predictive role of serum BDNF and anxiety-related
variables in changes in somatic symptoms post-escitalopram treatment in panic disorder …

Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis

H Hori, F Yoshida, I Ishida, J Matsuo, S Ogawa… - Journal of Affective …, 2024 - Elsevier
Background While depression has been associated with alterations in the hypothalamic-
pituitary adrenal (HPA) axis function, there is still controversy regarding the nature and …

CREB1 and BDNF gene polymorphisms are associated with early treatment response to escitalopram in panic disorder

J Yang, S Li, H Lv, W Wang, J Zhang, L Chu… - Journal of Affective …, 2021 - Elsevier
Objectives Increasing evidence shows that the alternations under escitalopram treatment for
Panic disorder (PD) patients are related to the cAMP response element-binding protein …

Gene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims

JM Pérez-Ortiz, MS García-Gutiérrez… - …, 2013 - Elsevier
Recent reports suggest that FKBP5 gene and its corresponding FKBP5 protein play a
relevant role in the regulation of anxiety and depression in animal models and human stress …

Serum BDNF levels are involved in the diagnosis and treatment response in patients with PD

R Li, J Li, Y Liu, D Li, L Chu, J Zhang, X Luo… - Journal of Affective …, 2023 - Elsevier
Background The study aimed to explore whether brain-derived neurotrophic factor (BDNF)
could be predictive for the diagnosis of panic disorder (PD) and to explore the association …

Effects of cytochrome P450 2C19 genetic polymorphisms on responses to escitalopram and levels of brain-derived neurotrophic factor in patients with panic disorder

Q He, Y Mei, Y Liu, Z Yuan, J Zhang… - Journal of clinical …, 2019 - journals.lww.com
Purpose/Background: The purpose of this study was to examine the relationships between
ytochrome P450 family 2 subfamily C member 19 (CYP2C19) polymorphisms, brain-derived …

Associations of DNA methylation of HPA axis-related genes and neuroendocrine abnormalities in panic disorder

Z Zou, M Xiang, Y Zhang, Y Huang, J Wang… - …, 2022 - Elsevier
Objective The purpose of this study was to investigate the role of aberrant DNA methylation
of hypothalamic-pituitary-adrenal (HPA) axis-related genes (CRHR1, CRHR2, CRH, FKBP5 …

[HTML][HTML] FKBP5 Gene Expression Predicts Antidepressant Treatment Outcome in Depression

M Ising, G Maccarrone, T Brückl, S Scheuer… - International Journal of …, 2019 - mdpi.com
Adverse experiences and chronic stress are well-known risk factors for the development of
major depression, and an impaired stress response regulation is frequently observed in …

Stress-induced cytokine levels in patients with panic disorder and its prediction of psychotherapy outcome

K Petrowski - Psychoneuroendocrinology, 2024 - Elsevier
Background An attenuated responsivity of the hypothalamus–hypophysis-adrenal (HPA)
axis upon challenge is a relatively consistent finding in panic disorder (PD). An altered HPA …