Update on inflammation, neurodegeneration, and immunoregulation in multiple sclerosis: therapeutic implications
JL Bennett, O Stüve - Clinical neuropharmacology, 2009 - journals.lww.com
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …
Multiple sclerosis and T lymphocytes: an entangled story
L Legroux, N Arbour - Journal of Neuroimmune Pharmacology, 2015 - Springer
Multiple sclerosis (MS) is the prototypic inflammatory disease of the central nervous system
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …
Pathogenic mechanisms associated with different clinical courses of multiple sclerosis
H Lassmann - Frontiers in immunology, 2019 - frontiersin.org
In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …
which may at later times transform into secondary progressive disease (SPMS). In a minority …
Inflammation in multiple sclerosis
S Haase, RA Linker - Therapeutic advances in neurological …, 2021 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) that is characterised pathologically by demyelination, gliosis, neuro-axonal damage …
(CNS) that is characterised pathologically by demyelination, gliosis, neuro-axonal damage …
Multiple sclerosis immunology: the healthy immune system vs the MS immune system
LH Kasper, J Shoemaker - Neurology, 2010 - AAN Enterprises
Multiple sclerosis (MS) is a debilitating autoimmune disease characterized by both
inflammation and axonal degeneration. The resulting demyelination and subsequent …
inflammation and axonal degeneration. The resulting demyelination and subsequent …
The good and the bad of neuroinflammation in multiple sclerosis
M Naegele, R Martin - Handbook of clinical neurology, 2014 - Elsevier
Multiple sclerosis (MS) is the most common inflammatory, demyelinating, neurodegenerative
disorder of the central nervous system (CNS). It is widely considered a T-cell mediated …
disorder of the central nervous system (CNS). It is widely considered a T-cell mediated …
New therapeutic approaches for multiple sclerosis
PL De Jager, DA Hafler - Annu. Rev. Med., 2007 - annualreviews.org
Although several therapies exist for multiple sclerosis (MS), the most common inflammatory
demyelinating disease of the central nervous system (CNS), there remains a large unmet …
demyelinating disease of the central nervous system (CNS), there remains a large unmet …
The immune pathogenesis of multiple sclerosis
R Weissert - Journal of Neuroimmune Pharmacology, 2013 - Springer
Multiple sclerosis is an autoimmune disease of the central nervous system (CNS) that leads
to changes of nerve conduction due to damage of CNS–resident cells, primarily …
to changes of nerve conduction due to damage of CNS–resident cells, primarily …
Myeloid cells—targets of medication in multiple sclerosis
Discussions of multiple sclerosis (MS) pathophysiology tend to focus on T cells and B cells
of the adaptive immune response. The innate immune system is less commonly considered …
of the adaptive immune response. The innate immune system is less commonly considered …
A basic overview of multiple sclerosis immunopathology
N Grigoriadis, V Van Pesch - European journal of neurology, 2015 - Wiley Online Library
Multiple sclerosis (MS) is a multi‐component disease characterized by inflammation,
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …