Regeneration and bioengineering of the gastrointestinal tract: current status and future perspectives
G Orlando, JE García-Arrarás, T Soker, C Booth… - Digestive and Liver …, 2012 - Elsevier
The present review aims to illustrate the strategies that are being implemented in
regenerative medicine to treat diseases that affect the digestive tract. Possible avenues are …
regenerative medicine to treat diseases that affect the digestive tract. Possible avenues are …
In-vivo oesophageal regeneration in a human being by use of a non-biological scaffold and extracellular matrix
KS Dua, WJ Hogan, AA Aadam, M Gasparri - The Lancet, 2016 - thelancet.com
Background Tissue-engineered extracellular matrix populated with autologous pluripotent
cells can result in de-novo organogenesis, but the technique is complex, not widely …
cells can result in de-novo organogenesis, but the technique is complex, not widely …
[HTML][HTML] First-in-human segmental esophageal reconstruction using a bioengineered mesenchymal stromal cell–seeded implant
JM Aho, S La Francesca, SD Olson, F Triolo… - JTO Clinical and …, 2021 - Elsevier
Introduction Resection and reconstruction of the esophagus remains fraught with morbidity
and mortality. Recently, data from a porcine reconstruction model revealed that segmental …
and mortality. Recently, data from a porcine reconstruction model revealed that segmental …
Tissue-engineered graft for circumferential esophageal reconstruction in rats
IG Kim, Y Wu, SA Park, H Cho, JW Shin… - JoVE (Journal of …, 2020 - jove.com
The use of biocompatible materials for circumferential esophageal reconstruction is a
technically challenging task in rats and requires an optimal implant technique with nutritional …
technically challenging task in rats and requires an optimal implant technique with nutritional …
Esophagus Tissue Engineering: Hybrid Approach with Esophageal Epithelium and Unidirectional Smooth Muscle Tissue Component Generation In Vitro
AK Saxena, K Kofler, H Ainödhofer… - Journal of Gastrointestinal …, 2009 - Springer
Purpose The aim of this study was to engineer the two main components of the esophagus
in vitro:(a) esophageal epithelium and (b) smooth muscle tissue. Furthermore,(a) …
in vitro:(a) esophageal epithelium and (b) smooth muscle tissue. Furthermore,(a) …
Early regenerative response in the intrathoracic porcine esophagus—The impact of the inflammation
L Jönsson, LG Friberg, V Gatzinsky… - Artificial …, 2014 - Wiley Online Library
In order to improve the treatment of children born with long‐gap esophageal atresia, a
porcine model was developed for studying esophageal regrowth using a bridging graft …
porcine model was developed for studying esophageal regrowth using a bridging graft …
Perfusion decellularization and characterization of esophagus with preserved folded mucosa for clinical reconstruction
S Sitthisang - 2021 - dr.ntu.edu.sg
Esophageal diseases necessitate the use of replacements or scaffolds to repair the
esophagus. As porcine esophagus is structurally and biochemically similar to that of …
esophagus. As porcine esophagus is structurally and biochemically similar to that of …
D1. 4 Oesophageal tissue engineering: preliminary evaluation of a 2 stage surgical approach in a mouse model
F Scottoni, L Urbani, C Camilli… - Archives of Disease in …, 2017 - adc.bmj.com
Background Oesophageal atresia is a birth defect occurring in approximately 1 in 2500 live
births. Tissue engineering is a promising therapeutic alternative for those patients requiring …
births. Tissue engineering is a promising therapeutic alternative for those patients requiring …
[HTML][HTML] Optimization of decellularization procedure in rat esophagus for possible development of a tissue engineered construct
P Mallis, P Chachlaki, M Katsimpoulas… - Bioengineering, 2018 - mdpi.com
Background: Current esophageal treatment is associated with significant morbidity. The gold
standard therapeutic strategies are stomach interposition or autografts derived from the …
standard therapeutic strategies are stomach interposition or autografts derived from the …
A new era: endoscopic tissue transplantation
CL Leggett, EC Gorospe, L Lutzke… - Current opinion in …, 2013 - journals.lww.com
The immediate foreseeable application of tissue engineering in gastrointestinal endoscopy
is in the field of mucosal repair after acute injury. Tissue regeneration can be achieved …
is in the field of mucosal repair after acute injury. Tissue regeneration can be achieved …