The field of tissue engineering encompasses efforts to construct functional biological
elements using cells, biomaterials, or their combination [1]. While most definitions of tissue …

Introduction: Oesophageal replacement by the colon or the stomach for malignant and
benign oesophageal diseases exposes to significant morbidity and mortality. Aim: In that …

Functions of the gastrointestinal tract include motility, digestion and absorption of nutrients.
These functions are mediated by several specialized cell types including smooth muscle …

Tissue engineering has emerged as a rapidly expanding approach to address the organ
shortage problem. It is an “interdisciplinary field that applies the principles and methods of …

The presence of a continuously renewing squamous cell epithelium that covers the
esophagus demonstrates the crucial role of a pluripotent stem cell population that regulates …

Background: Esophagus replacement presents major surgical challenges both in the
pediatric and in adult patients since the various surgical techniques presently employed are …

Background Esophageal replacement by the colon or the stomach for malignant and
nonmalignant esophageal diseases exposes to significant morbidity and mortality. In this …

The field of regenerative medicine is developing technologies that, in the near future, will
offer alternative approaches to either cure diseases affecting the gastrointestinal tract or …

Background Tissue engineering is an attractive alternative to conventional esophageal
replacement techniques using intra-abdominal organs which are associated with a …

Porous polymeric scaffolds have been widely employed as analogues of native extracellular
matrix to create a living construct that would mimic the complexities of human tissue function …