One of the greatest challenges for biomedical researchers is to gain greater insight into the
function of the brain. To find the best and the most relevant experimental model is …

The vesicular hypothesis of quantal acetylcholine release describes the process by which
discrete packages (or quanta) of the transmitter are released from nerve terminals through …

Some 50 years have elapsed since Elliot et al. and MacIntosh & Oborin first reported a
release of acetylcholine (ACh) from canine and feline cerebral cortices, respectively. In this …

Acetylcholine (ACh) is found in association with synaptic vesicle fractions obtained from
mammalian brain, diaphragm zyxwvutsrqpo and myenteric plexus, squid head ganglion …

Antibodies directed against the C-terminus of the rat vesicular acetylcholine transporter mark
expression of this specifically cholinergic protein in perinuclear regions of the soma and on …

The nature of the intraterminal compartments from which acetylcholine (ACh) is released
following presynaptic stimulation was investigated. This was pursued by examining the …

In order to develop another selective marker for cholinergic cell bodies and fibres, we have
raised a highly specific polyclonal antibody against a peptide derived from the C-terminus of …

Acetylcholine, the first chemical to be identified as a neurotransmitter, is packed in synaptic
vesicles by the activity of VAChT (vesicular acetylcholine transporter). A decrease in VAChT …

In the central nervous system, acetylcholine (ACh) is an important neurotransmitter related to
higher brain functions and some neurodegenerative diseases. It is released from cholinergic …

Rat VAChT cDNA was stably transfected into PC12 cells to generate cell clones
overexpressing different quantities of VAChT protein. Membrane fractions prepared from …