Evidence indicates that dysfunctional heterogeneous ribonucleoprotein A1 (hnRNPA1; A1)
contributes to the pathogenesis of neurodegeneration in multiple sclerosis. Understanding …

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is an RNA binding protein (RBP)
that is localized within neurons and plays crucial roles in RNA metabolism. Its importance in …

Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous
system. In recent years, it has become more evident that neurodegeneration, including …

Neurodegeneration is the primary driver of disease progression in multiple sclerosis (MS)
resulting in permanent disability, creating an urgent need to discover its underlying …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system with a
significant neurodegenerative component. Dysfunctional RNA-binding proteins (RBPs) are …

RNA binding proteins (RBPs) play a key role in cellular growth, homoeostasis and survival
and are tightly regulated. A deep understanding of their spatiotemporal regulation is needed …

Oligodendrocyte (OL) damage and death are prominent features of multiple sclerosis (MS)
pathology, yet mechanisms contributing to OL loss are incompletely understood …

Dysfunction of the RNA binding protein (RBP) heterogeneous nuclear ribonuclear protein
A1 (hnRNP A1) has been shown to contribute to the pathogenesis of neurodegenerative …

Some somatic single nucleotide variants (SNVs) are thought to be pathogenic, leading to
neurological disease. We hypothesized that heterogeneous nuclear ribonuclear protein A1 …

Objective Multiple sclerosis (MS) is the most common demyelinating disorder of the central
nervous system (CNS). Data suggest that antibodies to CNS targets contribute to the …