Under non-pathological conditions, human γδ T cells represent a small fraction of CD3+ T
cells in peripheral blood (1-10%). They constitute a unique subset of T lymphocytes that …

Summary γδ T cells are increasingly recognized as having important functional roles in a
range of disease scenarios such as infection, allergy, autoimmunity and cancer. With this …

γδ T cells expressing the Vγ9Vδ2 T cell receptor (TCR) account for 1–10% of CD3+
peripheral blood T lymphocytes. Vγ9Vδ2 T cells use their TCR as a pattern recognition …

As interest increases in harnessing the potential power of tissue‐resident cells for human
health and disease, γδ T cells have been thrust into the limelight due to their prevalence in …

Phenotypic and functional heterogeneity are the hallmarks of effector and memory T cells.
Upon antigen stimulation, γδ T cells differentiate into two major types of memory T cells …

The T cell receptor (TCR) repertoires of γδ T cells are very different to those of αβ T cells.
While the theoretical TCR repertoire diversity of γδ T cells is estimated to exceed the …

Human γδ T cells display potent responses to pathogens and malignancies. Of particular
interest are those expressing a γδ T-cell receptor (TCR) incorporating TCRδ-chain variable …

Abstract γδ T cells are a highly versatile immune lineage involved in host defense and
homeostasis, but questions remain around their heterogeneity, precise function and role …

γδ T cells are essential for immune defense and modulating physiological processes. While
they have the potential to recognize large numbers of antigens through somatic gene …

Summary γδ T cells comprise the third cell lineage of lymphocytes that use, like αβ T cells
and B cells, V (D) J gene rearrangement with the potential to generate a highly diverse T cell …