Here, polyethylenimine (PEI) modified silk fibroin nanoparticles (SFNPs) were prepared for
codelivery of doxorubicin (DOX) and survivin siRNA. The prepared NPs were characterized …

Poly γ-glutamic acid (γ-PGA) is attractive due to its desirable biological properties such as
nontoxicity, excellent biocompatibility, and minimal immunogenicity. Additionally, γ-PGA …

Purpose Chitosan, a natural and biocompatible cationic polymer, is an attractive carrier for
small interfering RNA (siRNA) delivery. The purpose of this study was to develop a chitosan …

The use of small interfering RNA (siRNA) in melanoma treatment remains limited owing to its
biological properties. Herein, we developed a carrier system containing hyaluronic acid and …

Background The co-delivery of chemotherapeutic agents and small interfering RNA (siRNA)
within one cargo can enhance the anticancer outcomes through its synergistic therapeutic …

Galactose modified trimethyl chitosan-cysteine (GTC) conjugates with various galactose
grafting densities were developed for oral delivery of Survivin shRNA-expression pDNA …

Inhibition of survivin by small interfering RNA (siRNA) can delay glioma growth. To enhance
the effect of survivin-siRNA on intercranial glioma, a conjugate of siRNA-survivin and single …

According to Globocan 2020, breast cancer is considered one of the most common cancers
affecting women and is one of the leading causes of death in over 100 countries. The …

Molecular therapy using a small interfering RNA (siRNA) has shown promise in the
development of novel therapeutics. Various formulations have been used for in vivo delivery …

Short interfering RNA (siRNA) possesses special ability of silencing specific gene. To
increase siRNA stability, transportation and its uptake by tumor cells, effective delivery to the …