Toad venom contains a large number of bufadienolides, which have a variety of
pharmacological activities, including antitumor, cardiovascular, anti-inflammatory, analgesic …

Toad venom (venenum bufonis, also called Chan'su) has been widely used for centuries in
China to treat different diseases, especially for cancer. Bufadienolides are mainly …

Cancer is the second leading cause of death worldwide. Specially, the high incidence rate
and prevalence of drug resistance have rendered prostate cancer (PCa) a great threat to …

Ethnopharmacological relevance Toad venom and toad skin have been widely used for
treating various cancers in China. Bufadienolides are regarded as the main anticancer …

Drying is a useful technique for extending the shelf-life of biological products and enabling
long-term storage; however, improper drying can reduce the chemical quality of the …

Bufadienolides are cardioactive C24 steroids with an α-pyrone ring at position C17. In the
last ten years, accumulating studies have revealed the anticancer activities of …

ChanSu (toad venom) is a traditional Chinese medicine for the treatment of serious liver and
gastric cancers. The major cytotoxic compounds in ChanSu are bufadienolides. In this …

A series of bufadienolides were isolated from the Bufo viridis toad venom, and their cytotoxic
activities against three human cancer cell lines (HeLa, HT-29, MCF7) and a non-cancer cell …

Bufadienolide, an essential member of the C-24 steroid family, is characterized by an α-
pyrone positioned at C-17. As the predominantly active constituent in traditional Chinese …

Toad venom, a traditional natural medicine, has been used for hundreds of years in China
for treating different diseases. Many studies have been performed to elucidate the …