[HTML][HTML] An integration-free iPSC line ZZUNEUi008-A derived from dermal fibroblasts of a child with cardiac valvular dysplasia carrying a mutation in FLNA gene
X Li, Y Lu, J Wang, M Liu, M Wang, L Hu, W Du… - Stem Cell Research, 2020 - Elsevier
FLNA gene encodes an actin-binding protein filamin A and mutations in FLNA can causes X-
Linked cardiac valvular dysplasia. In this study, we report the generation of ZZUNEUi008-A …
Linked cardiac valvular dysplasia. In this study, we report the generation of ZZUNEUi008-A …
[HTML][HTML] Generation of iPSC line (FAMRCi009-A) from patient with familial progressive cardiac conduction disorder carrying genetic variant FLNC p. Val2264Met
N Rodina, A Khudiakov, K Perepelina, A Muravyev… - Stem Cell Research, 2022 - Elsevier
Human iPSC cell line FAMRCi009-A was generated from a patient with restrictive
cardiomyopathy and congenital myopathy carrying FLNC p. Val2264Met genetic variant …
cardiomyopathy and congenital myopathy carrying FLNC p. Val2264Met genetic variant …
[HTML][HTML] Generation of a FLNA knockout hESC line (WAe009-AP) to model cardiac valvular dysplasia using CRISPR/Cas9
F Lu, Y Gao, E Li - Stem Cell Research, 2023 - Elsevier
The FLNA gene encodes the cytoskeletal protein filamin A which plays a key role in the
structure and function of the cardiac valves. Truncating FLNA mutations are associated with …
structure and function of the cardiac valves. Truncating FLNA mutations are associated with …
[HTML][HTML] Generation of a human iPSC line (HIMRi001-A) from a patient with filaminopathy
NM Daya, L Mavrommatis, H Zhuge, M Athamneh… - Stem Cell Research, 2023 - Elsevier
Here we introduce the human induced pluripotent stem cell (hiPSC) line HIMRi001-A
generated from cultured dermal fibroblasts of a 60-year-old male patient with a myofibrillar …
generated from cultured dermal fibroblasts of a 60-year-old male patient with a myofibrillar …
[HTML][HTML] Generation of iPSC line FAMRCi010-A from patient with restrictive cardiomyopathy carrying genetic variant FLNC p. Gly2011Arg
K Perepelina, A Khudiakov, N Rodina, A Boytsov… - Stem Cell Research, 2022 - Elsevier
Human iPSC cell line FAMRCi010-A was generated from a patient with restrictive
cardiomyopathy carrying FLNC p. Gly2011Arg genetic variant. Patient-specific peripheral …
cardiomyopathy carrying FLNC p. Gly2011Arg genetic variant. Patient-specific peripheral …
[HTML][HTML] Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying heterozygous FLNC mutations
A Kojic, H Kim, JV Guevara, S Ravada, K Sallam… - Stem cell …, 2022 - Elsevier
Dilated cardiomyopathy (DCM) is a heterogeneous cardiac disorder characterized by left
ventricular dilatation and dysfunction. Mutations in dozens of cardiac genes have been …
ventricular dilatation and dysfunction. Mutations in dozens of cardiac genes have been …
[HTML][HTML] Generation of a heterozygous FLNC mutation-carrying human iPSC line, USFi002-A, for modeling dilated cardiomyopathy
MA Argenziano, MB Angulo, MN Beidokhti, J Yang… - Stem Cell Research, 2021 - Elsevier
Dilated Cardiomyopathy (DCM) is one of the main causes of sudden cardiac death and
heart failure and is the leading indication for cardiac transplantation worldwide. Mutations in …
heart failure and is the leading indication for cardiac transplantation worldwide. Mutations in …
[HTML][HTML] Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with …
W Maurer, S Rebs, S Köhne, H Eberl, B Wollnik… - Stem Cell Research, 2024 - Elsevier
Filamin C (FLNC) is a highly important actin crosslinker and multi-adaptor protein in striated
skeletal and cardiac muscle. Mutations have been linked to a range of cardiomyopathy …
skeletal and cardiac muscle. Mutations have been linked to a range of cardiomyopathy …
[HTML][HTML] Generation of the human induced pluripotent stem cell lines (cmci009-a) from a patient with birt-hogg-dube syndrome (bhd) with heterozygous frameshift …
EJ Ko, S Cui, YJ Shin, SW Lim, KI Lee, JY Lee… - Stem Cell Research, 2021 - Elsevier
The human-induced pluripotent stem cell lines (hiPSCs)(CMCi009), derived from peripheral
blood mononuclear cells (PBMCs) of a 42-year-old woman who were diagnosed as Birt …
blood mononuclear cells (PBMCs) of a 42-year-old woman who were diagnosed as Birt …
[HTML][HTML] A CRISPR/Cas9 strategy for the generation of a FLNC knockout hESC line (WAe009-A-70) to model dilated cardiomyopathy and arrhythmogenic right …
Z Qin, L Sun, X Sun, H Su, X Gao - Stem Cell Research, 2021 - Elsevier
The FLNC gene encodes the sarcomeric protein filamin C which plays a central role in
cardiomyocytes. Truncating FLNC mutations (stop or frameshift etc.) also cause dilated …
cardiomyocytes. Truncating FLNC mutations (stop or frameshift etc.) also cause dilated …