The development of diabetes mellitus (DM) is accompanied by hyperglycemia-induced
oxidative stress. Hyperoside is a major bioactive component in Zanthoxylum bungeanum …

Diabetic nephropathy (DN) is a common complication of diabetes and the major cause of
chronic kidney disease. Cyanidin 3-glucoside (C3G) is the most widespread anthocyanin in …

Oxidative stress plays a major role in the development and progression of diabetic
nephropathy (DN). In this study, the potential protective effect of ginger (Zingiber officinale) …

Objective (s): Hyperglycemia promotes oxidative stress that plays a crucial role in the
pathogenesis of Diabetic nephropathy (DN). In this study, we investigated the synergism …

Hyperuricemia is an important risk factor of chronic kidney disease, metabolic syndrome and
cardiovascular disease. We aimed to assess the time-feature relationship of hyperuricemia …

Purpose To investigate the therapeutic effects and potential mechanisms of icariside II (ICA
II) on reversing diabetic nephropathy in streptozotocin (STZ)-induced type I diabetic rats …

Clozapine is widely employed in the treatment of schizophrenia. Compared with that of
atypical first-generation antipsychotics, atypical second-generation antipsychotics such as …

Background Osthole is a natural active ingredient extracted from the traditional Chinese
medicine Cnidium monnieri. It has been demonstrated to have anti-inflammatory, anti …

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease resulting in the destruction
of insulin producing β-cells of the pancreas, with consequent insulin deficiency and …

The urate oxidase (Uox) gene encodes uricase that in the rodent liver degrades uric acid
into allantoin, forming an obstacle for establishing stable mouse models of hyperuricemia …