Applications of Raman spectroscopy in the development of cell therapies: state of the art and future perspectives

S Rangan, HG Schulze, MZ Vardaki, MW Blades… - Analyst, 2020 - pubs.rsc.org
Therapies based on injecting living cells into patients offer a huge potential to cure many
degenerative and deadly diseases, with hundreds of clinical trials ongoing. Due to their …

[PDF][PDF] Applications of Raman micro-spectroscopy to stem cell technology: label-free molecular discrimination and monitoring cell differentiation

A Ghita, FC Pascut, V Sottile, C Denning… - EPJ Techniques and …, 2015 - Springer
Stem cell therapy is widely acknowledged as a key medical technology of the 21st century
which may provide treatments for many currently incurable diseases. These cells have an …

[HTML][HTML] Raman spectroscopy: an evolving technique for live cell studies

R Smith, KL Wright, L Ashton - Analyst, 2016 - pubs.rsc.org
One of the most exciting developments in Raman spectroscopy in the last decade has been
its application to cells and tissues for diagnostic and pharmaceutical applications, and in …

Raman detection and identification of normal and leukemic hematopoietic cells

S Managò, P Mirabelli, M Napolitano… - Journal of …, 2018 - Wiley Online Library
The analysis of leukocytes of peripheral blood is a crucial step in hematologic exams
commonly used for disease diagnosis and, typically, requires molecular labelling. In …

Raman microspectroscopy: a noninvasive tool for studies of individual living cells in vitro

I Notingher, LL Hench - Expert review of medical devices, 2006 - Taylor & Francis
There is an increasing need for noninvasive methods that are able to monitor individual live
cells in vitro, including in vitro testing of chemicals and pharmaceuticals, monitoring the …

[HTML][HTML] Raman spectroscopy and regenerative medicine: a review

KJI Ember, MA Hoeve, SL McAughtrie… - NPJ Regenerative …, 2017 - nature.com
The field of regenerative medicine spans a wide area of the biomedical landscape—from
single cell culture in laboratories to human whole-organ transplantation. To ensure that …

Progress in Raman spectroscopy in the fields of tissue engineering, diagnostics and toxicological testing

CA Owen, I Notingher, R Hill, M Stevens… - Journal of Materials …, 2006 - Springer
This review summarises progress in Raman spectroscopy and its application in diagnostics,
toxicological testing and tissue engineering. Applications of Raman spectroscopy in cell …

Advances in single cell Raman spectroscopy technologies for biological and environmental applications

D Wang, P He, Z Wang, G Li, N Majed, AZ Gu - Current opinion in …, 2020 - Elsevier
The increasing sophistication of single cell Raman spectroscopy (SCRS) via its integrations
with other advanced analytical techniques and modern data analytics, enable …

Identification of abnormal stem cells using Raman spectroscopy

L Harkness, SM Novikov, J Beermann… - Stem cells and …, 2012 - liebertpub.com
The clinical use of stem cells in cell-based therapeutics for degenerative diseases requires
development of criteria for defining normal stem cells to ensure safe transplantation …

Label‐free biochemical characterization of stem cells using vibrational spectroscopy

JW Chan, DK Lieu - Journal of biophotonics, 2009 - Wiley Online Library
Raman and infrared (IR) spectroscopy are two complementary vibrational spectroscopic
techniques that have experienced a tremendous growth in their use in biological and …