Insulin rapidly stimulates GLUT4 translocation and glucose transport in fat and muscle cells.
Signals from the occupied insulin receptor are translated into downstream signalling …

In muscle and fat cells, insulin stimulates the delivery of the glucose transporter GLUT4 from
an intracellular location to the cell surface, where it facilitates the reduction of plasma …

Insulin-regulated trafficking of the facilitative glucose transporter GLUT4 has been studied in
many cell types. The translocation of GLUT4 from intracellular membranes to the cell surface …

Insulin stimulation of glucose uptake into skeletal muscle and adipose tissues is achieved by
accelerating glucose transporter GLUT4 exocytosis from intracellular compartments to the …

One of the most important metabolic actions of insulin is catalysing glucose uptake into
skeletal muscle and adipose tissue. This is accomplished via activation of the …

GLUT4 is a mammalian facilitative glucose transporter that is highly expressed in adipose
tissue and striated muscle. In response to insulin, GLUT4 moves from intracellular storage …

The trafficking of the insulin-sensitive glucose transporter, GLUT4, is the paradigm of how
cells control the movement of membrane proteins through intricate pathways of transport in …

A pivotal metabolic function of insulin is the stimulation of glucose uptake into muscle and
adipose tissues. The discovery of the insulin-responsive glucose transporter type 4 (GLUT4) …

The search for the underlying mechanism through which insulin regulates glucose uptake
into peripheral tissues has unveiled a highly intricate network of molecules that function in …

Removal of excess glucose from the circulation involves the stimulation of glucose transport
into muscle and adipose tissue. In these tissues, the increase in glucose uptake depends on …