Extensive research has been conducted to elucidate and substantiate the crucial role of the
Renin-Angiotensin System (RAS) in the pathogenesis of hypertension, cardiovascular …

Diseases such as hypertension, atherosclerosis, hyperlipidemia, and diabetes are
associated with vascular functional and structural changes including endothelial …

Atherosclerosis is a chronic inflammatory disease associated with cardiovascular
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …

The renin-angiotensin system (RAS) has been demonstrated to play a critical role in the
initiation and progression of atherosclerosis, thereby contributing to development of …

Atherosclerosis has complex pathogenesis, which involves at least three serious aspects:
inflammation, lipid metabolism alterations, and endothelial injury. There are no effective …

Reactive oxygen species are oxygen derivates and play an active role in vascular biology.
These compounds are generated within the vascular wall, at the level of endothelial and …

Covalent modification of sulfur-containing amino acids in proteins by reactive oxygen
species (ROS) has been attracting attention as a major post-translational modification …

Reactive oxygen species (ROS) are proposed to induce cardiovascular diseases, such as
atherosclerosis, hypertension, restenosis, and fibrosis, through several mechanisms. One …

Hypertension is a major cardiovascular risk factor. Of the many processes involved in the
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …

Abstract Angiotensin II (Ang II), the major effector of the renin-angiotensin-aldosterone
system (RAAS), stimulates the production of reactive oxygen species (ROS) which are …