Almost invariably, humans become ill during primary infections with malaria parasites which
is a pathology associated with oxidative stress and perturbations in metabolism. Importantly …

Gut microbiota educate the local and distal immune system in early life to imprint long-term
immunological outcomes while maintaining the capacity to dynamically modulate the local …

Plasmodium falciparum is a protozoan parasite which causes malarial disease in humans.
Infections commonly occur in sub-Saharan Africa, a region with high rates of inadequate …

The big data movement has led to major advances in our ability to assess vast and complex
datasets related to the host and parasite during malaria infection. While host and parasite …

Abundant information refers to the role of microbiota in maintaining homeostasis by
assisting, improving, and regulating immunity in humans. Yet, the effect exerted by parasitic …

C57BL/6 mice are widely used for in vivo studies of immune function and metabolism in
mammals. In a previous study, it was observed that when C57BL/6 mice purchased from …

Malaria-associated bacteremia accounts for up to one-third of deaths from severe malaria,
and non-typhoidal Salmonella (NTS) has been reported as a major complication of severe …

Background Malaria infection in pregnancy is a major cause of maternal and foetal morbidity
and mortality worldwide. Mouse models for gestational malaria allow for the exploration of …

Host responses to infection with the malaria parasite Plasmodium falciparum vary among
individuals for reasons that are poorly understood. Here we reveal metabolic perturbations …

Background: Gastrointestinal symptoms are commonly associated with acute Plasmodium
spp infection. Malaria-associated enteritis may provide an opportunity for enteric pathogens …