The influence of parasite genetic factors on immune responses and development of severe
pathology of malaria is largely unknown. In this study, we performed genome-wide …

Plasmodium replicates within the liver prior to reaching the bloodstream and infecting red
blood cells. Because clinical manifestations of malaria only arise during the blood stage of …

Introduction Despite the advances in diagnosis and treatment, malaria has still not been
eradicated. Metabolic interactions between the host and Plasmodium may present novel …

Malaria is still a significant public health burden in the tropics. Infection with malaria causing
parasites results in a wide range of clinical disease presentations, from severe to …

Malaria-transmitting mosquitoes are continuously exposed to microbes, including their
midgut microbiota. This naturally acquired microbial flora can modulate the mosquito's …

Dysbiosis, developed upon antibiotic administration, results in loss of diversity and shifts in
the abundance of gut microbes. Doxycycline is a tetracycline antibiotic widely used for …

The microbiota of Anopheles mosquitoes influences malaria transmission. Antibiotics
ingested during a blood meal impact the mosquito microbiome and malaria transmission …

The susceptibility of Anopheles mosquitoes to Plasmodium infections relies on complex
interactions between the insect vector and the malaria parasite. A number of studies have …

Deciphering the mechanisms by which Plasmodium parasites develop inside hepatocytes is
an important step toward the understanding of malaria pathogenesis. We propose that the …

Infections by parasitic protozoans are largely neglected, despite threatening millions of
people, particularly in developing countries. With descriptions of the microbiota in humans, a …