Background The liver is responsible for a range of functions in vertebrates, such as
metabolism and immunity. In malaria, the liver plays a crucial role in the interaction between …

Altered interplay between gut mucosa and microbiota during treated HIV infection may
possibly contribute to increased bacterial translocation and chronic immune activation, both …

Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In
Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA …

In Plasmodium vivax malaria, mechanisms that trigger transition from uncomplicated to fatal
severe infections are obscure. In this multi-disciplinary study we have performed a …

Objectives To dissect the transcriptional networks underpinning immune cells responses
during primary Plasmodium vivax infection of healthy human adults. Methods We conducted …

While the liver and blood stages of the Plasmodium life cycle are commonly regarded as two
separate fields of malaria research, several studies have pointed towards the existence of a …

Despite significant advances in treating infectious diseases worldwide, morbidity and
mortality associated with pathogen infection remains extraordinarily high and represents a …

Purpose During Plasmodium berghei (P. berghei) infection, infected erythrocytes are
sequestered in gut tissues through microvascular circulation, leading to dysbiosis. This study …

Strong early inflammatory responses followed by a timely production of regulatory cytokines
are required to control malaria parasite multiplication without inducing major host pathology …