A dynamic actin-dependent nucleoskeleton and cell identity

T Venit, NH El Said, SR Mahmood… - The journal of …, 2021 - academic.oup.com
Actin is an essential regulator of cellular functions. In the eukaryotic cell nucleus, actin
regulates chromatin as a bona fide component of chromatin remodelling complexes, it …

Emerging roles of cytoskeletal proteins in regulating gene expression and genome organization during differentiation

X Xie, SR Mahmood, T Gjorgjieva, P Percipalle - Nucleus, 2020 - Taylor & Francis
In the eukaryotic cell nucleus, cytoskeletal proteins are emerging as essential players in
nuclear function. In particular, actin regulates chromatin as part of ATP-dependent chromatin …

Cytoskeletal proteins in the cell nucleus: a special nuclear actin perspective

P Percipalle, M Vartiainen - Molecular biology of the cell, 2019 - Am Soc Cell Biol
The emerging role of cytoskeletal proteins in the cell nucleus has become a new frontier in
cell biology. Actin and actin-binding proteins regulate chromatin and gene expression, but …

The role of nuclear actin in genome organization and gene expression regulation during differentiation

SR Mahmood, NH El Said, P Percipalle - Nuclear, Chromosomal, and …, 2022 - Springer
In the cell nucleus, actin participates in numerous essential processes. Actin is involved in
chromatin as part of specific ATP-dependent chromatin remodeling complexes and …

Nuclear actin dynamics in gene expression and genome organization

S Kyheröinen, MK Vartiainen - Seminars in cell & developmental biology, 2020 - Elsevier
Although best known from its functions in the cytoplasm, actin also localizes to the cell
nucleus, where it has been linked to many essential functions from regulation of gene …

Emerging properties and functions of actin and actin filaments inside the nucleus

S Ulferts, B Prajapati, R Grosse… - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
Recent years have provided considerable insights into the dynamic nature of the cell
nucleus, which is constantly reorganizing its genome, controlling its size and shape, as well …

An actin-based nucleoskeleton involved in gene regulation and genome organization

X Xie, P Percipalle - Biochemical and biophysical research communications, 2018 - Elsevier
In eukaryotic cells gene regulation is dependent on global genome organization. This is
achieved, in response to favorable environmental conditions, through spatial redistribution …

[HTML][HTML] Dynamizing nuclear actin filaments

M Plessner, R Grosse - Current opinion in cell biology, 2019 - Elsevier
While it is long known that actin is part of the nuclear proteome, its properties and functions
as regulated, functional and dynamically assembled actin filaments are only recently …

Nuclear actin: from discovery to function

DJ Kelpsch, TL Tootle - The Anatomical Record, 2018 - Wiley Online Library
While actin was discovered in the nucleus over 50 years ago, research lagged for decades
due to strong skepticism. The revitalization of research into nuclear actin occurred after it …

Actin nucleoskeleton in embryonic development and cellular differentiation

S Gunasekaran, Y Miyagawa, K Miyamoto - Current Opinion in Cell Biology, 2022 - Elsevier
Dynamic assembly and disassembly of actin proteins play a key role in the cytoskeleton, but
the cellular functions of actin are not only restricted to the cytoplasmic compartment. Recent …