Histone binding of ASF1 is required for fruiting body development but not for genome stability in the filamentous fungus Sordaria macrospora

J Breuer, T Busche, J Kalinowski, M Nowrousian - Mbio, 2024 - Am Soc Microbiol
The highly conserved eukaryotic histone chaperone ASF1 is involved in the assembly and
disassembly of nucleosomes during transcription, DNA replication, and repair. It was the first …

The histone chaperone ASF1 is essential for sexual development in the filamentous fungus Sordaria macrospora

S Gesing, D Schindler, B Fränzel… - Molecular …, 2012 - Wiley Online Library
Ascomycetes develop four major types of fruiting bodies that share a common ancestor, and
a set of common core genes most likely controls this process. One way to identify such …

The transcription factor PRO44 and the histone chaperone ASF1 regulate distinct aspects of multicellular development in the filamentous fungus Sordaria macrospora

DI Schumacher, R Lütkenhaus, F Altegoer, I Teichert… - BMC genetics, 2018 - Springer
Background Fungal fruiting bodies are complex three-dimensional structures that are formed
to protect and disperse the sexual spores. Their morphogenesis requires the concerted …

Functional analysis of chromatin-associated proteins in Sordaria macrospora reveals similar roles for RTT109 and ASF1 in development and DNA damage response

J Breuer, DEA Ferreira, M Kramer… - G3: Genes …, 2024 - academic.oup.com
We performed a functional analysis of two potential partners of ASF1, a highly conserved
histone chaperone that plays a crucial role in the sexual development and DNA damage …

[PDF][PDF] Structure and function of the conserved core of histone deposition protein Asf1

SM Daganzo, JP Erzberger, WM Lam, E Skordalakes… - Current Biology, 2003 - cell.com
Background: Asf1 is a ubiquitous eukaryotic histone binding and deposition protein that
mediates nucleosome formation in vitro and is required for genome stability in vivo. Studies …

The histone chaperone ASF1 localizes to active DNA replication forks to mediate efficient DNA replication

LL Schulz, JK Tyler - The FASEB journal, 2006 - Wiley Online Library
The packaging of the eukaryotic genome into chromatin is likely to regulate all processes
that occur on the DNA template. The assembly and disassembly of chromatin structures from …

Nuclear Chaperone ASF1 is Required for Gametogenesis in Arabidopsis thaliana

Y Min, JM Frost, Y Choi - Scientific Reports, 2019 - nature.com
Sexual reproduction in flowering plants is distinct from that in animals since gametogenesis
requires production of haploid spores, which divide and differentiate into specialised …

Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei

B Pascoalino, G Dindar… - Nucleic Acids …, 2014 - academic.oup.com
The anti-silencing function protein 1 (Asf1) is a chaperone that forms a complex with
histones H3 and H4 facilitating dimer deposition and removal from chromatin. Most …

Functional characterization of the developmental genes asm2, asm3, and spt3 required for fruiting body formation in the filamentous ascomycete Sordaria macrospora

R Lütkenhaus, J Breuer, M Nowrousian - Genetics, 2021 - academic.oup.com
The formation of fruiting bodies is one of the most complex developmental processes in
filamentous ascomycetes. It requires the development of sexual structures that give rise to …

Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells

F Sanematsu, Y Takami, HK Barman… - Journal of Biological …, 2006 - ASBMB
Asf1 (anti-silencing function 1), a well conserved protein from yeast to humans, acts as a
histone chaperone and is predicted to participate in a variety of chromatin-mediated cellular …