Evidence for the roles of oxidative stress, nitrosative stress and Nf-Kb activation in Tenofovir Disoproxil Fumarate (TDF) induced renal damage in rats
H Ramamoorthy, B Issac, P Abraham - BMC infectious diseases, 2012 - Springer
Background Nephrotoxicity is a dose limiting side effect of Tenofovir (TDF), a commonly
used anti-HIV drug. About 37-45% of patients on anti-HIV drugs suffer from renal damage …
used anti-HIV drug. About 37-45% of patients on anti-HIV drugs suffer from renal damage …
Role for NF-κB inflammatory signalling pathway in tenofovir disoproxil fumarate (TDF) induced renal damage in rats
H Ramamoorthy, P Abraham, B Isaac… - Food and Chemical …, 2017 - Elsevier
Nephrotoxicity due to tenofovir treatment of HIV patients has been reported. However, the
mechanism of tenofovir nephrotoxicity is not clear. NFκB is an important proinflammatory …
mechanism of tenofovir nephrotoxicity is not clear. NFκB is an important proinflammatory …
[图书][B] Tenofovir-Induced Nephrotoxicity: A Mechanistic Study
RA Murphey - 2007 - search.proquest.com
Tenofovir (TFV) is a reverse transcriptase inhibitor that is approved by the United States
Food and Drug Administration (FDA) to treat HIV and chronic Hepatitis B. It has a long half …
Food and Drug Administration (FDA) to treat HIV and chronic Hepatitis B. It has a long half …
Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate-induced mitochondrial damage and increased oxido-nitrosative stress in the …
P Abraham, H Ramamoorthy, B Isaac - Journal of biomedical science, 2013 - Springer
Background Nephrotoxicity is a dose limiting side effect of tenofovir, a reverse transcriptase
inhibitor that is used for the treatment of HIV infection. The mechanism of tenofovir …
inhibitor that is used for the treatment of HIV infection. The mechanism of tenofovir …
Treatment with β-blocker nebivolol ameliorates oxidative stress and endothelial dysfunction in tenofovir-induced nephrotoxicity in rats
MM Nascimento, DRD Bernardo… - Frontiers in …, 2022 - frontiersin.org
Background Tenofovir disoproxil fumarate (TDF), a widely prescribed component in
antiretroviral regimens, has been associated with nephrotoxicity. Nebivolol is a third …
antiretroviral regimens, has been associated with nephrotoxicity. Nebivolol is a third …
Mitochondrial pathway of apoptosis and necrosis contribute to tenofovir disoproxil fumarate–induced renal damage in rats
H Ramamoorthy, P Abraham, B Isaac… - Human & …, 2019 - journals.sagepub.com
Tenofovir disoproxil fumarate (TDF) is currently the only nucleotide analogue reverse-
transcriptase inhibitor that is approved by the Food and Drug administration (FDA), USA, for …
transcriptase inhibitor that is approved by the Food and Drug administration (FDA), USA, for …
Tenofovir-induced nephrotoxicity: incidence, mechanism, risk factors, prognosis and proposed agents for prevention
A Jafari, H Khalili, S Dashti-Khavidaki - European journal of clinical …, 2014 - Springer
Objective In this study, data regarding epidemiology, risk factors, pathogenesis and outcome
of tenofovir-induced nephrotoxicity will be reviewed, and current and future approaches for …
of tenofovir-induced nephrotoxicity will be reviewed, and current and future approaches for …
The Anti‐viral Agent Tenofovir Induces Oxidative Stress and Apoptosis in HK‐2 Cells
R Murphy, R Stafford, B Petrasovits… - The FASEB …, 2016 - Wiley Online Library
Tenofovir disproxil fumarate (Viread) is a highly effective HIV antiviral drug approved for
treating infections with Human Immunodeficiency Virus (HIV) and Hepatitis B. It is one of the …
treating infections with Human Immunodeficiency Virus (HIV) and Hepatitis B. It is one of the …
Cellular and Mitochondrial Damage by the Antiviral agent Tenofovir in Renal Epithelial Cells
MA Valentovic, KC Brown, R Murphy… - The FASEB …, 2022 - Wiley Online Library
Tenofovir disproxil fumarate (TDF) is a highly effective HIV antiviral drug approved for
treating Human Immunodeficiency Virus and Hepatitis B. It is one of the first line drugs used …
treating Human Immunodeficiency Virus and Hepatitis B. It is one of the first line drugs used …
Preclinical efficacy of melatonin in the amelioration of tenofovir nephrotoxicity by the attenuation of oxidative stress, nitrosative stress and inflammation in rats
H Ramamoorthy, P Abraham, B Isaac - Journal of basic and clinical …, 2014 - degruyter.com
Background: Nephrotoxicity is a dose-limiting side effect of long-term use of tenofovir, a
reverse transcriptase inhibitor that is used for the treatment of human immunodeficiency …
reverse transcriptase inhibitor that is used for the treatment of human immunodeficiency …