This study was designed to investigate the effect of 4 weeks of captopril treatment on cardiac
mass and performance in spontaneously hypertensive rats (SHR). Left (LV) and right (RV) …

The spontaneously hypertensive rat (SHR) exhibits both a compensated phase of cardiac
hypertrophy in which forward output is maintained despite persistently elevated systemic …

To determine whether chronic antihypertensive therapy reduces cardiac mass and improves
performance in spontaneously hypertensive rats (SHR) with marked left ventricular …

Spontaneously hypertensive rats (SHR) demonstrate elevated blood pressure, cardiac
hypertrophy, glucose intolerance, and insulin resistance compared with age-matched Wistar …

Cardiac function was studied in spontaneously breathing, adult spontaneously hypertensive
rats (SHR) and Wistar‐Kyoto normotensive rats (WKY). By rapid intravenous blood infusion …

To assess the influence of captopril on left ventricular mass in 24 normal Sprague-Dawley
rats, 12 were given high sodium (group 1) and 12 low sodium (group 2) diets. Half the rats …

While antihypertensive therapy is considered to be an important clinical intervention in
hypertensive patients, its effects on cardiac structure and function have not been intensely …

The purpose of the current study was to determine if early, short-term treatment of
spontaneously hypertensive rats (SHR) with captopril would cause a persistent attenuation …

To determine whether chronic antihypertensive therapy prevents the progression of cardiac
hypertrophy and the deterioration in cardiac performance observed in spontaneously …

To determine whether the electrocardiogram (ECG) could detect a reduction in ventricular
mass with chronic antihypertensive therapy, ECGs were obtained in two year old female …