Parameters on esophageal pH-impedance monitoring that predict outcomes of patients with gastroesophageal reflux disease

A Patel, GS Sayuk, CP Gyawali - Clinical Gastroenterology and Hepatology, 2015 - Elsevier
Background & Aims pH-impedance monitoring detects acid and nonacid reflux events, but
little is known about which parameters predict outcomes of different management strategies …

Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy

F Zerbib, S Roman, A Ropert… - Official journal of the …, 2006 - journals.lww.com
RESULTS One hundred fifty patients were included, 102 women (mean age 52±14 yr, range
16–84). Among the 79 patients off PPI, five did not report any symptom during the recording …

Acid-based parameters on pH-impedance testing predict symptom improvement with medical management better than impedance parameters

A Patel, GS Sayuk, PC Gyawali - Official journal of the American …, 2014 - journals.lww.com
OBJECTIVES: pH-impedance testing detects reflux events irrespective of pH, but its value in
predicting treatment outcome is unclear. We prospectively evaluated subjects treated …

Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms:'on'or 'off'proton pump inhibitor?

GJM Hemmink, AJ Bredenoord… - Official journal of the …, 2008 - journals.lww.com
BACKGROUND In patients with proton pump inhibitor (PPI)-resistant symptoms, ambulatory
24-h pH-impedance monitoring can be used to assess whether a relationship exists …

Esophageal impedance–pH monitoring

D Sifrim, F Fornari - Digestive and Liver Disease, 2008 - Elsevier
Classical techniques like endoscopy and esophageal pH-metry are routinely used to study
patients with symptoms related to gastroesophageal reflux disease (GERD). Although these …

Normal values of pharyngeal and esophageal 24-hour pH impedance in individuals on and off therapy and interobserver reproducibility

F Zerbib, S Roman, SB Des Varannes… - Clinical …, 2013 - Elsevier
BACKGROUND & AIMS: Combined pH and impedance monitoring can detect all types of
reflux episodes within the esophageal lumen and the pharynx. We performed a multicenter …

Efficacy of esophageal impedance/pH monitoring in patients with refractory gastroesophageal reflux disease, on and off therapy

JM Pritchett, M Aslam, JC Slaughter, RM Ness… - Clinical …, 2009 - Elsevier
BACKGROUND & AIMS: Intraluminal impedance monitoring has given new dimensions to
the diagnosis of reflux disease. However, there is no defined algorithm for evaluating …

Distal mean nocturnal baseline impedance on pH‐impedance monitoring predicts reflux burden and symptomatic outcome in gastro‐oesophageal reflux disease

A Patel, D Wang, N Sainani, GS Sayuk… - Alimentary …, 2016 - Wiley Online Library
Background Mean nocturnal baseline impedance (MNBI), a novel pH‐impedance metric,
may be a surrogate marker of reflux burden. Aim To assess the predictive value of MNBI on …

Prevalence, characteristics, and treatment outcomes of reflux hypersensitivity detected on pH‐impedance monitoring

A Patel, GS Sayuk, CP Gyawali - Neurogastroenterology & …, 2016 - Wiley Online Library
Background Positive symptom association probability (SAP) with physiologic esophageal
acid exposure time (AET) on pH‐impedance monitoring defines reflux hypersensitivity (RH) …

Clinical, but not oesophageal pH-impedance, profiles predict response to proton pump inhibitors in gastro-oesophageal reflux disease

F Zerbib, K Belhocine, M Simon, M Capdepont, F Mion… - Gut, 2012 - gut.bmj.com
Objective Approximately 30% of patients with gastro-oesophageal reflux disease (GORD) do
not achieve adequate symptom control with proton pump inhibitors (PPIs). The aim of this …