Bromocriptine: old drug, new formulation and new indication

RIG Holt, AH Barnett, CJ Bailey - Diabetes, Obesity and …, 2010 - Wiley Online Library
Bromocriptine is an ergot alkaloid dopamine D2 receptor agonist that has been used
extensively in the past to treat hyperprolactinaemia, galactorrhoea and Parkinsonism. It is …

Bromocriptine–unique formulation of a dopamine agonist for the treatment of type 2 diabetes

R Scranton, A Cincotta - Expert opinion on pharmacotherapy, 2010 - Taylor & Francis
Importance to the field: There is a large unmet need for new therapies to treat type 2
diabetes (T2DM) which reduce fasting and postprandial glucose without increasing insulin …

[HTML][HTML] Bromocriptine in type 2 diabetes mellitus

C Shivaprasad, S Kalra - Indian journal of endocrinology and …, 2011 - journals.lww.com
Bromocriptine mesylate quick-release was approved by the Food and Drug Administration
(FDA) in May 2009, for the treatment of type 2 diabetes. Bromocriptine is thought to act on …

Quick-release bromocriptine for treatment of type 2 diabetes

N Mikhail - Current drug delivery, 2011 - ingentaconnect.com
Quick-release bromocriptine (bromocriptine-QR)(Cycloset) was approved in 2009 for the
treatment of type 2 diabetes. The exact anti-diabetic mechanism of action of bromocriptine …

Bromocriptine mesylate for glycemic management in type 2 diabetes mellitus

JL Kerr, EM Timpe… - Annals of …, 2010 - journals.sagepub.com
Objective: To review the pharmacologic characteristics, safety, and efficacy of bromocriptine
mesylate for glycemic control in patients with type 2 diabetes mellitus. Data Sources: A …

Bromocriptine-QR therapy for the management of type 2 diabetes mellitus: developmental basis and therapeutic profile summary

P Raskin, AH Cincotta - Expert review of endocrinology & …, 2016 - Taylor & Francis
An extended series of studies indicate that endogenous phase shifts in circadian neuronal
input signaling to the biological clock system centered within the hypothalamic …

Bromocriptine improves glycaemic control and serum lipid profile in obese Type 2 diabetic subjects: a new approach in the treatment of diabetes

AH Cincotta, AH Meier, M Cincotta Jr - Expert opinion on …, 1999 - Taylor & Francis
Bromocriptine, a potent dopamine D2 receptor agonist, has been shown to reduce insulin
resistance, glucose intolerance and hyperlipidaemia in both numerous animal studies and …

Evidence-based practice use of quick-release bromocriptine across the natural history of type 2 diabetes mellitus

SS Schwartz, F Zangeneh - Postgraduate medicine, 2016 - Taylor & Francis
Objectives: To provide an evidence-based practice overview on the clinical use of
bromocriptine-quick release (QR) across the natural history of type 2 diabetes mellitus …

Bromocriptine: a sympatholytic, d2-dopamine agonist for the treatment of type 2 diabetes

RA DeFronzo - Diabetes care, 2011 - Am Diabetes Assoc
D2-dopamine agonist that has been approved for the treatment of type 2 diabetes. Based on
animal and human studies, timed bromocriptine administration within 2 h of awakening is …

The role of bromocriptine-QR in the management of type 2 diabetes expert panel recommendations

AJ Garber, L Blonde, ZT Bloomgarden, Y Handelsman… - Endocrine Practice, 2013 - Elsevier
Objective To review available data on the efficacy and safety of bromocriptine-QR (BQR)
and to consider its role in the management of Type 2 diabetes mellitus (T2DM). Methods …