Background Protection induced by acellular pertussis (aP) vaccines is partial and short-
lived, especially in teenagers, calling for novel immunization strategies. Methods We …

Background Recombinant pertussis vaccines inducing long-lasting immune responses
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …

Despite high vaccination coverage worldwide, pertussis has re-emerged in many countries.
This randomized, controlled, observer-blind phase I study and extension study in Belgium …

BACKGROUND: During the 1990s, the United States switched from combined diphtheria,
tetanus toxoids, whole-cell pertussis (DTwP) vaccines to combined acellular pertussis …

Background Increasing evidence shows that protection induced by acellular pertussis
vaccines is short-lived, requiring repeated booster vaccination to control pertussis disease …

Background The immunogenicity of acellular pertussis vaccines and persistence of immunity
after vaccination might be improved by using genetically inactivated pertussis toxin (PTgen) …

Importance There is accumulating literature on waning acellular pertussis vaccine–induced
immunity, confirming the results of studies assessing the duration of protection of pertussis …

The objective of this study was to evaluate reactogenicity and immunogenicity of the recently
US-licensed Connaught/BIKEN (C/B) acellular DTP (ADTP) vaccine as a booster for children …

Prior study children from a DTaP efficacy trial were recruited at ages 5 and 15 years to
randomized booster trials addressing immunogenicity and reactogenicity; 475 preschool …

Objective. To compare the immunogenicity and reactogenicity of a diphtheria and tetanus
toxoids and three-component acellular pertussis vaccine (DTaP) with a diphtheria and …