The removal of transmembrane proteins from the plasma membrane via endocytosis has
emerged as powerful strategy in the regulation of receptor signalling and molecule transport …

Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

Plasma membrane proteins play pivotal roles in mediating responses to endogenous and
environmental cues. Regulation of membrane protein levels and establishment of polarity …

In plants, the controlled absorption of soil nutrients by root epidermal cells is critical for
growth and development. IRON-REGULATED TRANSPORTER 1 (IRT1) is the main root …

In plants, the tight regulation of plasma membrane transporters is essential to maintain
nutrient homeostasis. The mechanisms controlling the abundance of transporters, and other …

The past two decades of research on plant iron nutrition have completed the casting of the
major transporters involved in iron uptake from the soil, long-distance transport, and …

Plants are the principal source of iron in most diets, yet iron availability often limits plant
growth. In response to iron deficiency, Arabidopsis roots induce the expression of the …

SUMMARY IRON‐REGULATED TRANSPORTER1 (IRT1) is the root high‐affinity ferrous
iron (Fe) uptake system and indispensable for the completion of the life cycle of Arabidopsis …

Plants require metals for essential functions ranging from respiration to photosynthesis.
These metals also contribute to the nutritional value of plants for both humans and livestock …

Main conclusion IRT1 intracellular dynamics and function are finely controlled through
protein–protein interactions. Abstract In plants, iron uptake from the soil is tightly regulated to …