[HTML][HTML] Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells

C Chrissian, E Camacho, JE Kelly, H Wang… - Journal of Biological …, 2020 - ASBMB
A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …

[HTML][HTML] Melanin deposition in two Cryptococcus species depends on cell-wall composition and flexibility

C Chrissian, E Camacho, MS Fu… - Journal of Biological …, 2020 - ASBMB
Cryptococcus neoformans and Cryptococcus gattii are two species complexes in the large
fungal genus Cryptococcus and are responsible for potentially lethal disseminated …

[HTML][HTML] Solid-state NMR reveals the carbon-based molecular architecture of Cryptococcus neoformans fungal eumelanins in the cell wall

S Chatterjee, R Prados-Rosales, B Itin… - Journal of Biological …, 2015 - ASBMB
Melanin pigments protect against both ionizing radiation and free radicals and have
potential soil remediation capabilities. Eumelanins produced by pathogenic Cryptococcus …

Using Solid-State NMR To Monitor the Molecular Consequences of Cryptococcus neoformans Melanization with Different Catecholamine Precursors

S Chatterjee, R Prados-Rosales, S Frases, B Itin… - Biochemistry, 2012 - ACS Publications
Melanins are a class of natural pigments associated with a wide range of biological
functions, including microbial virulence, energy transduction, and protection against solar …

Cryptococcus neoformans melanin and virulence: mechanism of action

Y Wang, P Aisen, A Casadevall - Infection and immunity, 1995 - Am Soc Microbiol
Black melanin-like pigments are produced by several neurotropic fungi, including
Cryptococcus neoformans. Pigment production is associated with virulence. In media …

[HTML][HTML] The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans

E Camacho, R Vij, C Chrissian… - Journal of Biological …, 2019 - ASBMB
Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …

Melanization in Cryptococcus neoformans requires complex regulation

RJB Cordero, E Camacho, A Casadevall - MBio, 2020 - Am Soc Microbiol
The fungal human pathogen Cryptococcus neoformans undergoes melanization in
response to nutrient starvation and exposure to exogenous melanin precursors …

Melanin and virulence in Cryptococcus neoformans

A Casadevall, AL Rosas, JD Nosanchuk - Current opinion in microbiology, 2000 - Elsevier
Melanin synthesis has been associated with virulence for the human pathogenic fungus
Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize …

Cryptococcus neoformans Can Utilize the Bacterial Melanin Precursor Homogentisic Acid for Fungal Melanogenesis

S Frases, A Salazar, E Dadachova… - Applied and …, 2007 - Am Soc Microbiol
Cryptococcus neoformans melanizes in the environment and in mammalian tissues, but the
process of melanization in either venue is mysterious given that this microbe produces …

Budding of melanized Cryptococcus neoformans in the presence or absence of l-dopa

JD Nosanchuk, A Casadevall - Microbiology, 2003 - microbiologyresearch.org
Cryptococcus neoformans is a pathogenic fungus that produces melanin when incubated in
the presence of certain phenolic substrates such as l-3, 4-dihydroxyphenylalanine (l-dopa) …